Chicago White Sox at Minnesota Twins odds, picks and prediction

Analyzing Monday’s Chicago White Sox at Minnesota Twins odds and lines, with MLB picks and predictions.

The Chicago White Sox (66-46) tussle with the Minnesota Twins (48-64) in the Monday night opener of a three-game series at Target Field. First pitch is scheduled for 8:10 p.m. ET. Let’s analyze the lines around the White Sox vs. Twins odds with MLB picks and predictions.

RHP Lucas Giolito is the projected starting pitcher for the White Sox. He has made 22 starts this season and is 8-8 with a 3.98 ERA, 1.16 WHIP, 10.1 K/9 and 2.7 BB/9 through 129 IP.

  • Has a long and effective history against current Twins hitters with a .640 OPS and .172 isolated power allowed. Has logged a 2.57 ERA in 14 IP against Minnesota in 2021 and has held batters to a .597 OPS in seven career games at Target Field.
  • Coming off a disastrous start against the Kansas City Royals with 3 home runs, and 6 earned runs allowed over 4 innings. Has a decent history in bouncing back after yielding 4-plus runs in a game.

RHP Beau Burrows is the projected starter for the Twins. He is a second-year Major Leaguer who was claimed off waivers from the Detroit Tigers in June. As a reliever only (Monday will mark his first career start), he has allowed 11 ER across 9 IP in 2021.

  • Has allowed 15 ER on 19 hits and 8 BB over 15 2/3 IP; has struck out 9.
  • Has thus far been an extreme fly-ball pitcher and has yielded 5 home runs in his career.
  • Making this start as an opener. The Twins own a 4.89 bullpen ERA to rank 26th MLB on the year.

White Sox at Twins odds, lines, picks and prediction

MLB odds courtesy of Tipico Sportsbook; access USA TODAY Sports for a full list. Odds last updated at 11:05 a.m. ET.

  • Money line: White Sox -220 (bet $220 to win $100) | Twins +180 (bet $100 to win $180)
  • Against the spread/ATS: White Sox -1.5 (-130) | Twins +1.5 (+105)
  • Over/Under: 9.5 (O: -125 | U: +100)

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Prediction

White Sox 4, Twins 3

Money line (ML)

The White Sox are coming off a three-game road sweep of the crosstown-rival Chicago Cubs. The Sox scored 21 runs in that series and own a .785 OPS over their last nine games.

The Twins head into this series off an impressive 3-1 series win at the Houston Astros. They may not be thrilled by what the schedule offers up next, as Chicago has taken 12 of 16 games from the Twins this season. The Pale Hose have outscored Minnesota, 109-65, along the way.

Peg the money line prices as bracketing the true odds on both sides: PASS.

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Run line/Against the spread (ATS)

The TWINS +1.5 (+105) play is perhaps worth some partial-unit action. Minnesota is back at home after a nine-game road trip and the Twins are 6-3 in series openers at home after returning from road trips. Minnesota has batted well at home after a slow start with a .782 OPS since June 24.

Five of the Twins’ last 6 games were decided by 2 or fewer runs. Before Chicago’s recent surge, the Sox were also playing a slew of close games.

Over/Under (O/U)

There isn’t much of a lean here, but what there is tilts toward the UNDER 9.5 (+100). An inward breeze, Giolito and a better-than-advertised Minnesota bullpen make for the slight shade toward a 7-to-9-run affair.

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