Chicago White Sox at Houston Astros odds, picks and predictions

Analyzing Friday’s Chicago White Sox at Houston Astros odds and lines, with MLB expert picks and predictions.

The Chicago White Sox (30-31) visit the Houston Astros (39-24) Friday for the start of a 3-game series at Minute Maid Park. First pitch is scheduled for 7:10 p.m. ET. Let’s analyze Tipico Sportsbook‘s lines around the White Sox vs. Astros odds with MLB picks and predictions.

Chicago went into Detroit this week and swept the Tigers 3-0. The White Sox are 6-4 straight up (SU) in their last 10 games after dropping 2 straight series at home vs. the Los Angeles Dodgers and Texas Rangers.

Houston won 2 of 3 at the Texas Rangers this week and the Astros are 5-5 SU in their last 10 after losing 2 consecutive series at home vs. the Seattle Mariners and Miami Marlins.

The Astros beat the White Sox 5-2 in last year’s regular-season series with a plus-12 run differential in those meetings. Houston eliminated Chicago in the 2021 American League Division Series (ALDS) 3-1 and the Astros outscored the White Sox 31-18 in the ALDS.

White Sox at Astros projected starters

RHP Lucas Giolito vs. LHP Framber Valdez

Giolito is 4-2 with a 3.88 ERA, 1.44 WHIP, 3.7 BB/9 and 11.8 K/9 in 53 1/3 IP over 10 starts.

  • Last start: No-decision in Chicago’s 11-9 loss at home vs. the Rangers Saturday with 5 IP, 4 ER, 6 H, 1 HR, 3 BB and 8 K.
  • 2021 vs. the Astros: One start, a complete-game 10-1 home win July 17 with 1 ER, 3 H, 1 HR, 0 BB and 8 K.

Valdez is 6-3 with a 2.64 ERA, 1.13 WHIP, 3.4 BB/9 and 7.3 K/9 in 75 IP over 12 starts.

  • Last start: Lost 5-1 Saturday at home vs. the Marlins with 6 IP, 2 ER, 4 H, 3 BB and 6 K.
  • 2021 vs. the White Sox: 1-1 with a 4.05 ERA (13 1/3 IP, 6 ER), 13 H, 3 HR, 4 BB and 9 K in 2 starts.

White Sox at Astros odds and lines

Odds provided by Tipico Sportsbook; access USA TODAY Sports Scores and Sports Betting Odds hub for a full list. Lines last updated at 12:11 p.m. ET.

  • Money line (ML): White Sox +135 (bet $100 to win $135) | Astros -170 (bet $170 to win $100)
  • Run line (RL)/Against the spread (ATS): White Sox +1.5 (-155) | Astros -1.5 (+125)
  • Over/Under (O/U): 7.5 (O: -122 | U: -102)

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White Sox at Astros picks and predictions

Prediction

Astros 5, White Sox 3

Money line

BET a half-unit only on the ASTROS (-170) at this price because their ML is dropping so we might get a better number closer to the first pitch.

Also, there’s more money on the White Sox (+135) but more bets have been placed on the Astros, according to Pregame.com. Typically, it’s wise to follow the money when it’s counter to the public since professional bettors put up a lot more dough than your average Joe.

That said, the Astros have a 3-phase edge over the White Sox in starting and relief pitching and hitting.

Valdez’s advanced pitching stats rank ahead of Giolito’s and Houston’s bullpen has a better WAR than Chicago’s (2.3-1.5) per FanGraphs.

The Astros beat the White Sox in several advanced hitting metrics including WAR (11.8-6.1) wRC+ (112-99), wOBA (.319-.303) and BB/K rate (0.48-0.32).

This is a profitable spot for the Astros who are 9-2 SU at home vs. right-handed starters as favorites of -160 or greater with a plus-23.2% return on investment.

Wait until closer to the first pitch for a better number on Houston and only “flat-BET” the ASTROS (-170) 1 unit instead of betting to win 1 unit.

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Run line/Against the spread

LEAN to the ASTROS -1.5 (+125) because of the aforementioned 3-phase edge and the plus-money payout on Houston’s RL.

However, I cannot fully get there on the Astros covering since the White Sox +1.5 (-155) are taking sharp action and are 9-6 RL as road underdogs.

Over/Under

PASS. 

The Astros are 3-8 O/U at home vs. righties as -160 ML favorites or greater but the White Sox are 4-0-2 O/U in Giolito’s 6 road starts this season and this is a sharp total.

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