The Chicago White Sox (49-48) and Colorado Rockies (44-54) wrap their 2-game interleague series Wednesday at Coors Field in Denver. First pitch is scheduled for 3:10 p.m. ET. Let’s analyze Tipico Sportsbook‘s lines around the White Sox vs. Rockies odds with MLB picks and predictions.
Season series: The White Sox won 2-1 Wednesday in the first meeting of the season.
The White Sox have won 3 games in a row, and look for their first series sweep since winning all 3 games in a series at the San Francisco Giants July 1-3. Chicago is 8-3 in interleague play.
The Rockies have dropped 5 of their last 6 outings. Colorado has registered a 6-9 record against the American League this season.
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White Sox at Rockies projected starters
RHP Lucas Giolito vs. RHP Antonio Senzatela
Giolito (6-6, 5.12 ERA) makes his 18th start. He has a 1.46 WHIP, 3.2 BB/9 and 10.2 K/9 through 91 1/3 IP.
- Has posted a 4.27 ERA and .259 opponent batting average in 10 road starts vs. a 6.28 ERA and .314 opponent BA in 7 home outings.
- Is 2-2 with a 4.91 ERA and 22 K through 22 IP across 4 starts in July.
Senzatela (3-5, 4.98 ERA) makes his 15th start. He has a 1.79 WHIP, 2.2 BB/9 and 5.3 K/9 through 65 IP.
- Is a dismal 0-1 with a 7.71 ERA and .355 opponent BA in 7 IP across 2 starts in July.
- Has posted a 3-2 record, 4.02 ERA and .367 opponent BA with 18 K through 40 1/3 IP across 9 starts at Coors Field in 2022.
White Sox at Rockies odds and lines
Odds provided by Tipico Sportsbook; access USA TODAY Sports Scores and Sports Betting Odds hub for a full list. Lines last updated at 5:28 a.m. ET.
- Money line (ML): White Sox -140 (bet $140 to win $100) | Rockies +115 (bet $100 to win $115)
- Run line (RL)/Against the spread (ATS): White Sox -1.5 (+105) | Rockies +1.5 (-130)
- Over/Under (O/U): 11.5 (O: -122 | U: -102)
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White Sox at Rockies picks and predictions
Prediction
White Sox 8, Rockies 5
Money line
The WHITE SOX (-140) are a decent play as a moderate favorite against the struggling Rockies. Chicago has fared well against NL teams this season, and Giolito has at least held his own, especially on the road.
Senzatela has won just once in his last 10 starts dating back to April 29, and he has allowed 3 or more ER in 3 straight outings, and 6 of his last 9 starts.
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Run line/Against the spread
The WHITE SOX -1.5 (+105) are a better play on the run line at plus money. Chicago won 2-1 in a well-pitched series opener Tuesday, but this game should have a lot more offense for both sides.
Over/Under
The OVER 11.5 (-122) is the lean in this interleague series finale. Even though the Under hit Tuesday, the Over is 4-1-2 in the last 7 games for the Pale Hose.
The Over has cashed in 5 of the previous 6 outings for the Rockies against winning teams. The Over is 2-0 in the past 2 starts for Senzatela, and 10-4 in his 14 starts this season.
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