Chicago White Sox at Cleveland Guardians odds, picks and predictions

Analyzing Friday’s Chicago White Sox at Cleveland Guardians odds and lines, with MLB expert picks and predictions.

The Chicago White Sox (61-58) and Cleveland Guardians (63-55) open a 3-game set at Progressive Field. Friday’s series opener is slated for a 7:05 p.m. ET first pitch. Let’s analyze Tipico Sportsbook‘s lines around the White Sox vs. Guardians odds with MLB picks and predictions.

Season series: Cleveland leads 8-5

The White Sox have lost 2 straight after winning 5 in a row from Aug. 12-16. Chicago had a fine 2nd-half ERA of 3.39 until coughing up 21 runs in Thursday’s loss to the Houston Astros.

The Guardians have pitched themselves to a 12-6 record since July 31. Cleveland owns a 3.24 ERA, 1.09 WHIP over that productive stretch.

Play our free daily Pick’em Challenge and win! Play now!

White Sox at Guardians projected starters

RHP Lance Lynn vs. RHP Triston McKenzie

Lynn (3-5, 5.62 ERA) owns a 1.25 WHIP, 1.5 BB/9 and 9.5 K/9 through 65 2/3 IP in 12 starts.

  • Has a 3.34 ERA, 0.91 WHIP over his last 5 starts
  • Owns a 6.92 ERA in 5 starts against Cleveland since last May

McKenzie (8-9, 3.14 ERA) has a 0.97 WHIP, 2.3 BB/9 and 8.3 K/9 through 134 2/3 IP in 22 games (21 starts).

  • Owns a 6.65 ERA in his last 5 starts against Chicago
  • Has come on strong in July and August with a 1.82 ERA in his last 8 starts
  • Has a 2.82 ERA at home

White Sox at Guardians odds and lines

Odds provided by Tipico Sportsbook; access USA TODAY Sports Scores and Sports Betting Odds hub for a full list. Lines last updated at 10:37 a.m. ET.

  • Money line: White Sox +110 (bet $100 to win $110) | Guardians -135 (bet $135 to win $100)
  • Run line (RL)/Against the spread (ATS): White Sox +1.5 (-190) | Guardians -1.5 (+155)
  • Over/Under (O/U): 7.5 (O: -107 | U: -115)

Exclusive USA TODAY Network offer: Deposit $10 or more, get $200 in instant bet credits at Tipico Sportsbook! New customer offer in CO and NJ. 21+, see Tipico.com for Terms and Conditions. Place your legal, online sports bets at Tipico. Let’s make this interesting. Bet now!

White Sox at Guardians picks and predictions

Prediction

White Sox 4, Guardians 3

Money line

Lynn has been undone by a .312 batting average on balls in play and a very low strand rate. The veteran righty has yielded a .355 BABIP with runners in scoring position.

McKenzie has some BABIP numbers that sway the other way, and he’s been more fortunate in 3rd-time around situations.

It all spells some leverage for the visiting team in a series of 2 teams closely matched when it comes to pitting real production against expected production based on analytics.

TAKE CHICAGO (+110).

Win your fantasy baseball league with BaseballHQ.com. For decades, BHQ has been helping players just like you win! Use the couple code SBW22 for 20% OFF full-season subscription. New customer offer; expires 8/31/2022. Subscribe today and start winning!

Run line/Against the spread

Bettors not scared off buy the bullpen disparity of late between these clubs (last 30 days: Cleveland 2.31 ERA , Chicago 5.11) should consider the WHITE SOX +1.5 (-190).

Over/Under

PASS. No leverage on either side of this total and these prices.

Bet legally online with a trusted partner: Tipico Sportsbook, Sportsbook Wire’s official sportsbook partner in CO and NJ. Bet now!

If you’re looking for more sports betting picks and tips, access all of our content at SportsbookWire.com and BetFTW, or try out our USA TODAY Parlay Calculator. Please gamble responsibly.

Follow SportsbookWire on Twitter and like us on Facebook.

Additional MLB coverage:
BaseballHQ Fantasy Baseball
BaseballPress.com: Your source for every MLB lineup

Gannett may earn revenue from Tipico for audience referrals to betting services. Tipico has no influence over nor are any such revenues in any way dependent on or linked to the newsrooms or news coverage. See Tipico.com for Terms and Conditions. 21+ only. Gambling problem? Call 1-800-GAMBLER (NJ), 1-800-522-4700 (CO).

[mm-video type=playlist id=01fb7dafw2b08817yr player_id=none image=https://sportsbookwire.usatoday.com/wp-content/plugins/mm-video/images/playlist-icon.png]

[lawrence-newsletter]

[lawrence-auto-related count=3 category=1372]