The Chargers had their final practice today ahead their matchup on Saturday against the Patriots.
Running back Gus Edwards (ankle), linebacker Denzel Perryman (groin) and offensive lineman Trey Pipkins III (hip) have been ruled out for Sunday.
Head coach Jim Harbaugh said Edwards reaggravated his ankle injury from last week’s game against the Broncos.
Perryman also reaggravated his groin injury last week.
Running back J.K. Dobbins (knee), who was designated to return from injured reserve, is questionable. Harbaugh said Dobbins had a good week of practice.
Tight end Will Dissly (shoulder), tight end Hayden Hurst (illness) and safety Elijah Molden (knee) are questionable for Week 17.
Cornerback Cam Hart, who did not play last week against Denver due to a concussion, does not carry an injury designation and will play.