Cardinals open as road underdogs in Week 1 vs. Titans

The Arizona Cardinals open the 2021 season as 2.5-point road underdogs against the Tennessee Titans.

[mm-video type=video id=01f5hkq3vatjmhxh9q23 playlist_id=01eqbw7fa4ahbvdd03 player_id=none image=https://images2.minutemediacdn.com/image/upload/video/thumbnail/mmplus/01f5hkq3vatjmhxh9q23/01f5hkq3vatjmhxh9q23-a413f34a83176f7b15aefd4c90cd4079.jpg]

The 2021 schedule is out for the Arizona Cardinals and they will open the season on the road against the Tennessee Titans, the AFC South champs last season. They have not faced the Titans since 2017.

According to BetMGM, Arizona opens as underdogs on the road in the season opener.

The Titans are favored by 2.5 points for bets against the spread.

On the money line, betting for an outright winner, the Titans are favored at -140 (bet $140 to win $100). That gives Tennessee 58.33% implied odds of winning.

The Cardinals are the underdogs to win straight up at +115 (bet $100 to win $115). They have 46.51% implied odds of winning.

The total for the game is set at 51.5 points.

The Cardinals went 8-8 overall last season and were 4-4 on the road. They went 7-9 against the spread (ATS) and 5-11 O/U (over/under the total)

Tennessee was 11-5 last year and 5-3 at home. They were 7-10 ATS and 12-4-1 O/U.


Gannett may earn revenue from audience referrals to betting services. Newsrooms are independent of this relationship and there is no influence on news coverage.


[vertical-gallery id=451497]

Listen to the latest from Cards Wire’s Jess Root on his podcast, Rise Up, See Red. Subscribe on Apple podcasts or Spotify.

Latest show:


Previous shows:


and