Cardinals to face 7 of NFL’s 11 best RBs in 2021

Starting with Derrick Henry in Week 1 and Dalvin Cook in Week 2, the Arizona Cardinals’ run defense will be tested early and often in 2021.

The Arizona Cardinals defense will be tested on many fronts this coming season. They will face many of the top tight ends, outside receivers and slot receivers.

Based on Touchdown Wire’s rankings of the 11 best running backs in the NFL, the Cardinals will also face seven of them this coming season.

The defense, especially the defensive line and the young inside linebacker pairing of Zaven Collins and Isaiah Simmons will be tested.

See which top backs they will face below.

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