Buffalo Bills at Cincinnati Bengals odds, picks and predictions

Analyzing Monday’s Buffalo Bills at Cincinnati Bengals odds and lines, with expert NFL picks, predictions and best bets.

The Buffalo Bills (12-3) battle the Cincinnati Bengals (11-4) at Paycor Stadium on Monday night. Kickoff from Cincinnati is set for 8:30 p.m. ET (ESPN). Below, we analyze Tipico Sportsbook’s lines around the Bills vs. Bengals odds, and make our expert NFL picks and predictions.

The Bills are on a 6-game winning streak, most recently blowing out the Bears 35-13, covering as 14-point road favorites. Buffalo is 7-7-1 against the spread (ATS) and has only covered 3 times in their last 9 games. The Bills have the 4th-best offense in the NFL for points scored per game (28) and the 2nd-best defense for points allowed (17.5 PPG).

Cincinnati beat New England 22-18 last week, extending its win streak to 7 games and covering as 3-point road favorites. The Bengals have covered 9 of their last 10 games are are 12-3 ATS overall. The offense ranks 5th in passing yards per game (269.2) while the defense ranks 7th in rushing yards allowed per game (106.4).

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Bills at Bengals odds

Provided by Tipico Sportsbook; access USA TODAY Sports Scores and Sports Betting Odds hub for a full list. Lines last updated Sunday at 2:31 p.m. ET.

  • Moneyline (ML): Bills -120 (bet $120 to win $100) | Bengals +100 (bet $100 to win $100)
  • Against the spread (ATS): Bills -1.5 (-108) | Bengals +1.5 (-112)
  • Over/Under (O/U): 49.5 (O: -109 | U: -111)

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Bills at Bengals key injuries

Bills

  • DE Boogie Basham (calf) questionable
  • TE Dawson Knox (hip) questionable
  • OLB Matt Milano (knee) questionable
  • NT Jordan Phillips (shoulder) questionable
  • FS Jordan Poyer (knee) questionable

Bengals

  • OT La’el Collins (knee) out
  • DE Sam Hubbard (calf) questionable

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Bills at Bengals picks and predictions

Prediction

Bengals 27, Bills 20

Moneyline

BET BENGALS (+100).

This season, Buffalo is ranked 30th in turnovers (24), whereas Cincinnati has a top-10 defense in the takeaway category (20).

The Bills QB Josh Allen has thrown multiple interceptions 4 times in his previous 9 games. This could lead to a few game-changing turnovers and is becoming too consistent for the MVP-hopeful quarterback.

Against the spread

PASS.

The underdog is 7-2 ATS in the last 9 meetings between these 2 which bodes well for a Cincinnati win. While the Bengals have been hot against the spread this season and worthy of a play in this primetime battle, the moneyline is a more preferable play.

Over/Under

LEAN UNDER 49.5 (-111).

The Bills are 5-10 O/U and the Bengals are 5-9-1 O/U with just 1 of their previous 5 games hitting the Over. In a game that is predicted to be rainy, with 2 top-10 rush defenses, points will be at a premium.

The Under is 7-1 in the Bills’ last 8 road games and 7-0 in the Bengals’ last 7 games against a team with a winning record.

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