Boston Red Sox at Cleveland Guardians odds, picks and predictions

Analyzing Friday’s Boston Red Sox at Cleveland Guardians odds and lines, with MLB expert picks and predictions.

The Cleveland Guardians (36-28) host the Boston Red Sox (39-31) for the start of a 3-game series at Progressive Field with Friday’s 1st pitch scheduled for 7:10 p.m. ET. Let’s analyze Tipico Sportsbook‘s lines around the Red Sox vs. Guardians odds with MLB picks and predictions.

Boston is 8-2 straight up (SU) in the last 10 games and is on a 4-game winning streak.

Cleveland is also 8-2 SU in the last 10 and is tied atop the AL Central with the Minnesota Twins.

The Red Sox lead the season series 4-2 and have outscored the Guardians by 38-23 in the 6 games.

Red Sox at Guardians projected starters

RHP Nick Pivetta vs. RHP Cal Quantrill    

Pivetta is 7-5 with a 3.31 ERA, 1.09 WHIP, 3.2 BB/9 and 9.0 K/9 in 81 2/3 IP over 14 starts.

  • Last start: Won 6-4 Sunday at home vs. the St. Louis Cardinals with 7 IP, 1 ER, 4 H, 4 BB and 10 K.
  • 2022 road splits: 3-3 with a 3.86 ERA, 1.08 WHIP, 4 HR and 9.5 K/9 in 39 2/3 IP over 7 starts.

Quantrill is 4-4 with a 3.77 ERA, 1.26 WHIP, 2.9 BB/9 and 5.5 K/9 in 71 2/3 IP over 12 starts.

  • Last start: Lost 7-1 Saturday at the Los Angeles Dodgers with 5 IP, 5 ER, 10 H, 1 HR, 1 BB and 4 K.
  • 2021 vs. the Red Sox: 0-1 with a 4.15 ERA (13 IP, 6 ER), 13 H, 4 HR, 4 BB and 12 K in 2 starts.

Red Sox at Guardians odds and lines

Odds provided by Tipico Sportsbook; access USA TODAY Sports Scores and Sports Betting Odds hub for a full list. Lines last updated at 11:13 a.m. ET.

  • Money line (ML): Red Sox -125 (bet $125 to win $100) | Guardians +102 (bet $100 to win $102)
  • Run line (RL)/Against the spread (ATS): Red Sox -1.5 (+130) | Guardians +1.5 (-160)
  • Over/Under (O/U): 8.5 (O: -135 | U: +110)

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Red Sox at Guardians picks and predictions

Prediction

Guardians 5, Red Sox 4

Money line

BET the GUARDIANS (+102) because they have a 3-phase edge over the Red Sox (-120) in starting and relief pitching and hitting.

Quantrill grades much higher than Pivetta in several advanced pitching metrics such as exit velocity (65-9%), hard-hit rate (76-15%) and chase rate (80-22%), according to Statcast.

Furthermore, Cleveland’s bullpen is better than Boston’s by ERA (3.80-2.94), xFIP (4.07-3.54), hard-hit rate (41.5-37.5%) and K/BB rate (2.88-2.62), per FanGraphs.

Finally, the Guardians are 23-19 SU against right-handed starters while the Red Sox are 26-27 SU vs. righties. Also, Cleveland’s lineup outperforms Boston’s vs. right-handed pitching in wRC+ (109-102), wOBA (.319-.315) and BB/K rate (0.44-0.35), according to FanGraphs.

BET 1 unit on the GUARDIANS (+102).

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Run line/Against the spread

PASS.

This is a good spot for the Red Sox -1.5 (+135) since they are 6-1 RL following a rest day and 4-1 RL as road favorites vs. teams with a winning record since the beginning of last season. As much as I’d like some insurance for Cleveland’s ML, the Guardians +1.5 (-170) is just too expensive.

Over/Under

LEAN OVER 8.5 (-135), if at all.

Red Sox-Guardians are 13-6-1 O/U in their last 20 meetings, Boston is 4-2-1 O/U following a rest day and Cleveland is 6-2 O/U as home underdogs vs. teams with a winning record.

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