Week 16 is going to go a long way to determining playoff positioning for the top teams and draft slotting for the lesser teams because of the way the schedule lays out. Of the 16 Week 16 games, 14 of them will pit conference opponents, and seven of those will be division matchups.
Odds provided by BetMGM Sportsbook
Denver Broncos (+120) at Los Angeles Chargers (-145)
The Over/Under is pretty low (42 points at -110 for both Over and Under). In their last four games (all wins), the Broncos have scored 38, 29, 41, and 31 points. The Chargers have topped this number in each of their last four home games. Take Over 42 points (-110).
Houston Texans (+135) at Kansas City Chiefs (-160)
The Chiefs are slight home favorites (3 points at -110 for both teams). Patrick Mahomes will try to play through his injury and, while the Texans are in the playoffs, heading north to play outdoors is far from an ideal scenario. Take the Chiefs and lay 3 points (-110).
Pittsburgh Steelers (+225) at Baltimore Ravens (-275)
The Ravens are big favorites (6 points at -110 for both teams). The Steelers have won the last four meetings by scores of 16-13, 17-10, 17-10, and 18-16. The Ravens are capable of blowing them out but haven’t showed, losing eight of nine meetings since 2020. Take the Steelers plus 6 points (-110).
New York Giants (+350) at Atlanta Falcons (-450)
The Falcons are huge favorites (8.5 points at -110 for both). The move to Michael Penix Jr. should be a solid one, because the Giants have no film to look at, and New York’s offense isn’t going to threaten Atlanta’s defense. Take the Falcons and lay 8.5 points (-110).
Detroit Lions (-300) at Chicago Bears (+240)
The Lions are solid road favorites (6.5 points at -110 for both teams). In their eight-game losing streak, the Bears have scored 15 or fewer points five times. Even with key defensive injuries, the Lions have the horses to win by a touchdown or more. Take the Lions and lay 6.5 points (-110).
Cleveland Browns (+310) at Cincinnati Bengals (-400)
The Bengals are big favorites (7.5 points at -115 Browns, -105 Bengals). With Cleveland making another quarterback change, and the Bengals putting up 27 or more points in each of their last five games, the Browns just can’t hang with them. Take the Bengals and lay 7.5 points (-105).
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Tennessee Titans (+155) at Indianapolis Colts (-190)
The Over/Under is low (42 points at -110 for both). The Titans defense is awful, allowing 27 or more points in six of its last nine games. The Colts aren’t much better, allowing 24 or more points in their last five games. Take Over 42 points (-110).
Los Angeles Rams (-190) at New York Jets (+155)
The Rams are road favorites (3.5 points at -110 for both). Three of New York’s four wins have come against the Tennessee Titans, New England Patriots and Jacksonville Jaguars. The Rams are hot and have momentum on their side, even in a bad road situation. Take the Rams and lay 3.5 points (-110).
Philadelphia Eagles (-185) at Washington Commanders (+150)
The Eagles are iffy favorites (3.5 points at -105 Eagles, -115 Commanders). The Eagles are fighting for No. 1 seed in the NFC and are playing like it. In the last month, they have put down the Los Angeles Rams, Baltimore Ravens and Pittsburgh Steelers – much less already beating the Commanders before that. Take the Eagles and lay 3.5 points (-105).
Arizona Cardinals (-225) at Carolina Panthers (+180)
The Over/Under is steep (47 points at -110 for both). The Panthers are taking baby steps toward respectability, and the Cardinals have wild up and down swings. This looks like a game decided by field goals, not touchdowns. Take Under 47 points (-110).
Minnesota Vikings (-160) at Seattle Seahawks (+135)
The Vikings are road favorites (-3 points at -110 for both). By Week 16 standards, the Seahawks have faced two teams with Super Bowl potential. They lost to the Detroit Lions by 13 and the Buffalo Bills by 21. Take the Vikings plus 3 points (-110).
New England Patriots (+650) at Buffalo Bills (-1000)
Buffalo is a gigantic favorite that should be avoided. The O/U suggests the Patriots are going to do their part (46.5 points at -115 Over, -105 Under). Buffalo has a penchant for scoring 30-plus, but the Patriots won’t help. Take Under 46.5 points.
Jacksonville Jaguars (-105) at Las Vegas Raiders (-115)
The Raiders are 1-point favorites. This is the most unwatchable game in the league, and if there is tanking for a QB in 2024, it should be on display Sunday. Take the Jaguars on the moneyline (-105).
San Francisco 49ers (+100) at Miami Dolphins (-120)
The Dolphins are favored, but the dead-in-the-water 49ers aren’t dead yet. Both teams had Super Bowl aspirations that have long since expired. The Niners have been there before. Take the 49ers on the moneyline (+100).
Tampa Bay Buccaneers (-210) at Dallas Cowboys (+170)
The Bucs are strong road favorites (4 points at -110 for both teams). The Cowboys won’t be in the playoffs, but being a 4-point dog at home against a pedestrian Bucs team doesn’t seem right. Take the Cowboys plus 4 points (-110).
New Orleans Saints (+650) at Green Bay Packers (-1000)
The Packers are huge favorites (14.5 points at -120 Saints, -110 Packers). Green Bay will likely finish third in its own division, but that doesn’t mean they can’t beat down a lesser team that wants nothing to do with Lambeau in December. Take the Packers and lay 14.5 points (-110).