Baltimore Orioles at Houston Astros odds, picks and predictions

Analyzing Friday’s Baltimore Orioles at Houston Astros odds and lines, with MLB expert picks and predictions.

The Baltimore Orioles (65-59) and Houston Astros (81-45) meet Friday at Minute Maid Park with 1st pitch in the opener of a 3-game series scheduled for 8:10 p.m. ET. Let’s analyze Tipico Sportsbook‘s lines around the Orioles vs. Astros odds with MLB picks and predictions.

Season series: First meeting; the AL foes split 6 games in 2021

The Orioles are coming off a 4-3 homestand. Baltimore bats struggled on the club’s last road trip (Aug. 11-17), notching a .631 OPS against Toronto Blue Jays and Tampa Bay Rays pitching.

The Astros are coming off a 3-game home sweep of the Minnesota Twins. Houston has won 4 in a row, and Astros batting and pitching alike have been dialed in in the club going 10-4 since Aug. 11. Houston owns an .816 OPS and 3.34 ERA  over that stretch.

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Orioles at Astros projected starters

RHP Kyle Bradish vs. RHP Lance McCullers, Jr.

Bradish (1-5, 6.25 ERA) owns a 1.65 WHIP, 3.4 BB/9 and 9.1 K/9 through 72 IP in 15 starts.

  • Has a 4.21 ERA over his last 5 starts
  • The 25-year-old rookie notched a 3.66 ERA in 54 career minor league games

McCullers (1-1, 2.45 ERA) has a 1.45 WHIP, 5.7 BB/9 and 9.0 K/9 in 11 IP.

  • Making his 3rd start off a long-term stay on the IL (forearm)
  • Owns a 3.55 ERA, 1.27 WHIP in 124 career games

Orioles at Astros odds and lines

Odds provided by Tipico Sportsbook; access USA TODAY Sports Scores and Sports Betting Odds hub for a full list. Lines last updated at 10:58 a.m. ET.

  • Money line: Orioles +160 (bet $100 to win $160) | Astros -200 (bet $200 to win $100)
  • Run line (RL)/Against the spread (ATS): Orioles +1.5 (-130) | Astros -1.5 (+105)
  • Over/Under (O/U): 8.5 (O: +100 | U: -125)

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Orioles at Astros picks and predictions

Prediction

Astros 5, Orioles 3

Money line

The on-a-streak, performing-well-in-diverse-facets-of-the-game Astros are a lean up to -185 or so. But some extra juice drowns out the profit margin at the current tag.

STEER CLEAR.

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Run line/Against the spread

ASTROS -1.5 (+105) is the most profitable side in this match-up.

Bradish has gone to the edge of his pitch-count leash each of his last 2 starts. He’s had trouble against righty bats, and that’s what Houston piles up most nights.

Over/Under

Mixed signals on both sides of the ball and on both teams: PASS.

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