Atlanta Falcons at San Francisco 49ers odds, picks and prediction

Analyzing Sunday’s Atlanta Falcons at San Francisco 49ers odds and lines, with expert NFL picks, predictions and best bets.

The Atlanta Falcons (6-7) will try to improve their playoff chances this weekend with a Sunday late afternoon game against the San Francisco 49ers (7-6). Kickoff is at 4:05 p.m. ET at Levis Stadium. Below, we look at the Falcons vs. 49ers odds and lines, and make our best NFL picks, predictions and bets.

The 49ers have won four of their last five games and are currently the No. 6 seed in the NFC. QB Jimmy Garoppolo has thrown multiple touchdown passes in five of the last six games. They beat the Cincinnati Bengals 26-23 in overtime in Week 15.

The Falcons are one of five 6-7 teams in the NFC vying for a wild card berth. However, they have the second-worst point differential in the conference at -108. They are averaging 18.8 points per game but have won two of their last three games.

Falcons at 49ers odds, spread and lines

Odds provided by Tipico Sportsbook; access USA TODAY Sports Scores and Sports Betting Odds hub for a full list. Lines last updated Saturday at 2:33 p.m. ET.

  • Money line: Falcons +330 (bet $100 to win $330) | 49ers -450 (bet $450 to win $100)
  • Against the spread (ATS): Falcons +9.5 (-110) | 49ers -9.5 (-110)
  • Over/Under (O/U): 46.5 (O: -110 | U: -110)

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Falcons at 49ers key injuries

Falcons

  • LB Dante Fowler (calf) questionable
  • Erik Harris (chest) out

49ers

  • RB Elijah Mitchell (concussion, knee) out
  • LB Dre Greenlaw (groin) out
  • LB Azeez Al-Shaair (elbow) doubtful
  • DT D.J. Jones (knee) questionable
  • DT Maurice Hurst (calf) out
  • Jaquiski Tartt (glute) questionable
  • CB Ambry Thomas (concussion) questionable

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Falcons at 49ers odds, lines, predictions and picks

Prediction

49ers 31, Falcons 23

Money line

The 49ers are playing some of their best ball this season, especially offensively, while the Falcons have yet to string together multiple wins this season.

They have, though, won five of seven games on the road this season, while the 49ers are 2-4 at home.

With the line for the 49ers priced where it is, PASS on the money line.

Against the spread

Both the Falcons and the 49ers are 6-7 ATS this season.

The 49ers are 5-2 ATS in their last seven games.

The Falcons have faced a double-digit spread twice this season already. They covered the spread both times.

I like the 49ers to win but I don’t think it will be a blowout. Take the FALCONS +9.5 (-110).

Over/Under

The 49ers are 7-6 O/U this season and the Falcons are 6-7 O/U. The 49ers have surpassed 30 points in four of their last seven games.

The Falcons’ last game hit the Over but the previous four stayed Under the projected total.

But since I think the 49ers will crack the 30-point mark and I think the Falcons will keep the deficit under 10 points, take OVER 46.5 (-110).

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