Arizona Cardinals at New Orleans Saints odds and lines: Winston hopes to seize QB starting job

Assessing the odds and lines for Saturday’s Arizona Cardinals at New Orleans Saints NFL preseason Week 3 matchup.

The New Orleans Saints (1-1) host the Arizona Cardinals (1-1) Saturday for both teams’ preseason finale at Caesars Superdome with kickoff scheduled for 8 p.m. ET. Below, we look at the Cardinals vs. Saints odds and lines.

Arizona lost 17-10 to the Kansas City Chiefs as 3.5-point underdogs Friday with the Cardinals averaging a whole yard fewer per play less than the Chiefs and K.C. converting 15 more first downs (28-13). Arizona QB Kyler Murray completed just 1 of 4 passes for 2 yards in his first preseason game.

The Saints’ first-stringers jumped out to a 14-0 first-quarter lead on the Jacksonville Jaguars in their second preseason game Monday as QB Jameis Winston completed 9 of 10 passes for 123 yards, 2 touchdowns and 0 interceptions. New Orleans went on to win 23-21 but failed to cover as a 4-point favorite.

Cardinals at Saints: Odds, spread and lines

Odds via Tipico Sportsbook; access USA TODAY Sports’ betting odds for a full list. Lines last updated Tuesday at 2:30 p.m. ET.

  • Money line: Cardinals +145 (bet $100 to win $145) | Saints -180 (bet $180 to win $100)
  • Against the spread/ATS: Cardinals +3.5, -125 (bet $125 to win $100) | Saints -3.5, +100 (bet $100 to win $100)
  • Total: 34.5, Over -105 (bet $105 to win $100) | Under -115 (bet $115 to win $100)

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2021 Preseason betting stats:

  • ATS: Cardinals 1-1 | Saints 0-2
  • O/U: Cardinals 0-2 | Saints 1-1

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Arizona covers the spread by losing by 3 or fewer points, winning outright or playing to a tie. The Cardinals have a 40.82% implied win probability with the +145 money line odds, which equates to 2.45 decimal odds and 29/20 fractional odds.

The Saints (-180) have an implied win probability of 64.29%. Those odds in decimal form are 1.56 or 5/9 in fractional odds. New Orleans -3.5 (+100) means the Saints must win by 4 or more points in order to cover the spread.

The total sits at 34.5 with the Under juiced up to -115 and the Over sitting at -105. The Cardinals and Saints need to combine for 35 or more total points to cash an Over bet but if 34 or fewer points are scored then the Under wins.

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