Arizona Cardinals at LA Rams odds, picks and predictions

Analyzing Saturday’s Arizona Cardinals at LA Rams odds and lines, with expert NFL picks and predictions.

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The Arizona Cardinals (7-8) are on the road against the LA Rams (9-6) this week, a special Saturday night showdown at SoFi Stadium. This NFC West matchup will kick off at 8:15 p.m. ET (NFL Network). Let’s analyze BetMGM Sportsbook’s NFL odds around the Cardinals vs. Rams odds, and make our expert NFL picks and predictions.

The Cardinals were shockingly eliminated from playoff contention in Week 16 when they lost to the Carolina Panthers in overtime, 36-30, as 5.5-point favorites. Had the Cardinals beat the Panthers, this game would have major playoff implications in the NFC West. Instead, only the Rams have something to play for.

LA can clinch the division title this weekend with a win over the Cardinals and help from 4 other teams. It’s not the clearest path to the postseason in Week 17, but it’s possible for the Rams to lock up a playoff berth by Sunday. In their most recent game, the Rams beat the New York Jets, 19-9, Sunday afternoon, which was their fourth straight win.

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Cardinals at Rams odds

Provided by BetMGM Sportsbook; access USA TODAY Sports Scores and Sports Betting Odds hub for a full list of NFL odds. Lines last updated Friday at 10:10 a.m. ET.

  • Moneyline (ML): Cardinals +240 (bet $100 to win $240) | Rams -300 (bet $300 to win $100)
  • Against the spread (ATS): Cardinals +6.5 (-105) | Rams -6.5 (-115)
  • Over/Under (O/U): 48 (O: -110 | U: -110)

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Cardinals at Rams key injuries

Cardinals

  • RB Trey Benson (ankle) questionable
  • LB Baron Browning (neck) questionable
  • RB James Conner (knee) probable
  • K Matt Prater (knee) out

Rams

  • RT Rob Havenstein (shoulder) questionable

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Cardinals at Rams picks and predictions

Prediction

Rams 24, Cardinals 17

Moneyline

PASS on the moneyline. The Rams are too heavily favored at -300 to be worth betting, and with the Cardinals having nothing to play for, Arizona is also a risky play on the ML.

Against the spread

The Cardinals are just 2-3 ATS in their last 5 games, losing 4 of them outright to their opponent. The Rams, meanwhile, are the much hotter team. They’re riding a 4-game winning streak and have covered the spread in all of them, twice as favorites and twice as underdogs.

The Rams are big favorites at -6.5, but they’re finding ways to win and will now be out of the elements after back-to-back games in the rain and freezing temperatures. The offense should perform much better than it has in the last 2 games when the Rams scored 19 and 12 points.

BET RAMS -6.5 (-115) to cover the spread and beat the Cardinals by a touchdown.

Over/Under

The total in Rams games has only gone over 48 points once in the last 4 weeks. The same goes for the Cardinals.

LA is notorious for starting games slowly and Arizona’s offense has had dry spells in the last month, putting up 22 or fewer points in 3 of its last 5 games.

BET UNDER 48 (-110).

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