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The second week of the preseason continues with the Arizona Cardinals on the road against the Indianapolis Colts Saturday. Kickoff from Lucas Oil Stadium is at 7 p.m. ET. Below, we analyze BetMGM Sportsbook’s lines around the Cardinals vs. Colts odds, and make our expert NFL picks and predictions.
The Cardinals opened the preseason with a 16-14 last-second loss to the visiting New Orleans Saints Aug. 10, covering as 3-point underdogs. The Under (38.5) cashed in.
The Colts also lost their preseason opener, falling 34-30 at home to the Denver Broncos as 1.5-point favorites Sunday as the Over (38.5) hit.
Cardinals at Colts odds
Provided by BetMGM Sportsbook; access USA TODAY Sports Scores and Sports Betting Odds hub for a full list. Lines last updated at 8:40 a.m. ET.
- Moneyline (ML): Cardinals +110 (bet $100 to win $110) | Colts -135 (bet $135 to win $100)
- Against the spread (ATS): Cardinals +1.5 (-110) | Colts -1.5 (-110)
- Over/Under (O/U): 36.5 (O: -110 | U: -110)
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Cardinals at Colts picks and predictions
Prediction
Cardinals 23, Colts 20
Moneyline
Neither team will play their starters this weekend. It will be a battle of backups and guys just trying to make an NFL roster.
There is never a reliable way to handicap preseason games. They are volatile.
The only way to bet the preseason is to simply take the plus odds on the moneyline on a few games and hope you hit at least half of them.
BET CARDINALS (+110).
Against the spread
Again, with games being decided late by players who largely won’t be on NFL rosters next month, there is no way to feel confident in a winning outcome, especially when no starters will play.
PASS.
Over/Under
The Cardinals only allowed 16 points last week and only scored 14, but all 14 came in the 2nd half.
The Colts allowed 34 last week. There are concerns with their defensive depth.
With no starters playing, expect both teams to be in the 20s.
BET OVER 36.5 (-110).
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For more sports betting picks and tips, check out SportsbookWire.com and BetFTW.
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