Arizona Cardinals at Carolina Panthers odds, picks and predictions

Analyzing Sunday’s Arizona Cardinals at Carolina Panthers odds and lines, with expert NFL picks and predictions.

[gambcom-standard rankid=”4141″ ]

The Arizona Cardinals (7-7) and the Carolina Panthers (3-11) meet Sunday in a Week 16 game at Bank of America Stadium. Kickoff is scheduled for 1 p.m. ET (FOX). Let’s analyze BetMGM Sportsbook’s NFL odds around the Cardinals vs. Panthers odds, and make our expert NFL picks and predictions.

The Cardinals have managed to win just once in the past 4 games on the road, although Arizona is a respectable 4-2 against the spread (ATS) away from home this season.

Arizona scored a 30-17 win over the New England Patriots as a 6-point favorite as the Over (46) just came in last Sunday. It was the highest scoring total since a 41-10 win in Week 2 against the LA Rams.

Carolina suffered a 30-14 loss to the visiting Dallas Cowboys last Sunday, halting a 5-game cover streak. Since a 20-17 OT win against the New York Giants in Munich, Germany in Week 10, the Panthers have dropped 4 in a row. The Over is 3-1 in the past 4 games, and 5-2 across the past 7 outings.

Play our free daily Pick’em Challenge and win! Play now!

Cardinals at Panthers odds

Provided by BetMGM Sportsbook; access USA TODAY Sports Scores and Sports Betting Odds hub for a full list of NFL odds. Lines last updated Saturday at 10:39 p.m. ET.

  • Moneyline (ML): Cardinals -250 (bet $250 to win $100) | Panthers +190 (bet $100 to win $190)
  • Against the spread (ATS): Cardinals -5 (-110) | Panthers +5 (-110)
  • Over/Under (O/U): 47 (O: -110 | U: -110)

[gambcom-standard rankid=”4132″ ]

Cardinals at Panthers key injuries

Cardinals

  • RB Trey Benson (ankle) out
  • OG Evan Brown (neck) questionable
  • RB DeeJay Dallas (illness) questionable
  • OL Paris Johnson Jr. (knee) out
  • CB Elijah Jones (ankle) out
  • DL Roy Lopez (ankle) questionable
  • LB Jesse Luketa (thigh) out
  • CB Sean Murphy-Bunting (hand) questionable
  • PK Matt Prater (knee) out
  • LB Mack Wilson Sr. (concussion) out

Panthers

  • LB Jadeveon Clowney (illness, knee) questionable
  • WR Jalen Coker (quadriceps) questionable
  • OT Ikem Ekwonu (illness) questionable
  • OG Robert Hunt (illness) questionable
  • WR Xavier Legette (hip) out
  • WR David Moore (concussion) questionable
  • DE A’Shawn Robinson (knee) questionable

FOOTBALL NEVER STOPS
Live games, analysis and more 7 days a week: Get ESPN+

Cardinals at Panthers picks and predictions

Prediction

Cardinals 30, Panthers 19

Moneyline

The Cardinals (-250) will cost you 2 1/2 times your potential return, and that’s a little on the risky side for a road team.

Arizona is 7-7 and battling for a division title, while Carolina is 3-11 and simply playing on the string. However, the Panthers have been very competitive lately, with 5 of the past 6 games decided by a single score, so it won’t be easy.

PASS.

Against the spread

The CARDINALS -5 (-110) are laying a rather moderate number on the road. However, the Cardinals have a dangerous dual-threat QB in Murray, and the Panthers +5 (-110) have had a devil of a time trying to stop the run this season.

Carolina ranks last in the NFL allowing 173.0 yards per game on the road, and it is also last in the league with 29.9 PPG allowed. Murray and Conner should have huge days in Charlotte.

Over/Under

OVER 47 (-110) is the lean, but go with a half-unit play at most.

The total has ended up going high in 3 of the past 4 games, while cashing at a 9-3 pace in the past 12 outings for Carolina. The Panthers defense has really struggled this season in all facets.

Arizona has hit high in the past 2 games, averaging 24.0 PPG on offense, with 23.5 PPG allowed on defense in the span.

[gambcom-standard rankid=”6305″ ]

For more sports betting picks and tips, check out SportsbookWire.com and BetFTW.

Follow Kevin J. Erickson on Twitter/X. Follow SportsbookWire on Twitter/X and like us on Facebook.

Access more NFL coverage:
BetFTW | TheHuddle Fantasy Football | BearsWire | BengalsWire | BillsWire | BroncosWire | BrownsWire | BucsWire | CardsWire | ChargersWire | ChiefsWire | ColtsWire | CommandersWire | CowboysWire | DolphinsWire | EaglesWire | FalconsWire | GiantsWire | JaguarsWire | JetsWire | LionsWire | NinersWire | PackersWire | PanthersWire | PatriotsWire | RaidersWire | RamsWire | RavensWire | SaintsWire | SeahawksWire | SteelersWire | TexansWireTitansWire | VikingsWire | DraftWire | TouchdownWire | ListWire

[lawrence-newsletter]

[lawrence-auto-related count=3 category=1367]