ALERT: Christian McCaffrey is INACTIVE

Make sure to get CMC out of your lineups tonight.

In a surprise move, San Francisco 49ers running back Christian McCaffrey (calf, Achilles) will not play tonight, contrary to reports from just a couple of days ago that said he would see a full workload.

Backup running back Jordan Mason is expected to start and see a large share of the touches. Look for more rushing from WR Deebo Samuel, and rookie running back Isaac Guerendo could see a handful of carries, too.

Mason is worthy of an RB2/flex start, whereas Guerendo is a dice roll for a desperate gamer looking for a TD flier. If you can’t play either of those backs, there’s a chance Braelon Allen from the New York Jets is still on your wire, and he could see a couple of touches behind Breece Hall.