First look: Arizona Cardinals at Carolina Panthers odds and lines

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The Arizona Cardinals (7-7) hit the road in Week 16 to face the Carolina Panthers (3-11). Kickoff is Sunday at 1 p.m. ET from Bank of America Stadium (FOX). Below, we look at Cardinals vs. Panthers odds from BetMGM Sportsbook’s NFL odds before making our expert NFL picks and predictions later in the week.

The Cardinals snapped a 3-game losing streak Sunday, beating the New England Patriots 30-17 at home. Arizona covered as a 6-point favorite and the Over (46) snuck in by a point. RB James Conner rushed for 110 yards and 2 TDs in the victory. The win kept the Cards 1 game behind the co-leading LA Rams and Seattle Seahawks in the NFC West.

The Panthers lost their fourth consecutive game, suffering a 30-14 home loss as 2.5-point favorites to the Dallas Cowboys Sunday. The Over (41.5) hit in this one, too. QB Bryce Young (19 of 28, 219 passing yards, 1 TD) was picked off twice and the Carolina offense mustered only 235 yards. Meanwhile, the defense allowed 410 yards. Dallas QB Cooper Rush (18 of 29, 214 passing yards) threw 3 TD passes against no interceptions and RB Rico Dowdle finished with 149 rushing yards.

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Cardinals at Panthers odds

Provided by BetMGM Sportsbook; access USA TODAY Sports Scores and Sports Betting Odds hub for a full list of NFL odds. Lines last updated Monday at 9:49 p.m. ET.

Moneyline (ML): Cardinals -225 (bet $225 to win $100) | Panthers +180 (bet $100 to win $180)
Against the spread (ATS): Cardinals -4 (-110) | Panthers +4 (-110)
Over/Under (O/U): 47 (O: -115 | U: -105)

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2024 betting stats

ML: Cardinals 7-7 | Panthers 3-11
ATS: Cardinals 9-5 | Panthers 6-8
O/U: Cardinals 6-7-1 | Panthers 10-4

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Cardinals vs. Panthers head-to-head

The Panthers lead the all-time series 14-6, including 2-1 in the playoffs.

They last met in Week 4 of the 2022-23 season, a 26-16 Arizona win in Charlotte as a 2.5-point underdog. QB Kyler Murray (207 passing yards) threw 2 TD passes in the win. It snapped a streak of 6 straight wins in the series by the Panthers. Murray is 1-2 in 3 career starts against the Panthers with 7 TD passes, 3 interceptions and 1 rushing TD.

This will be Young’s first career start against the Cardinals.

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For more sports betting picks and tips, check out SportsbookWire.com and BetFTW.

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