Betting the NFL Line: Week 13

A league-wide view into the best wagers to make for NFL Week 13 action.

The NFL continues its plan to co-opt all major holidays – official and made up – including three games on Thanksgiving Day, a Black Friday matchup, a full state of games on Sunday, and a primetime Cyber Monday game.

If you eat during NFL games, Thanksgiving leftovers will be exhausted quicker than usual. Happy Thanksgiving from all of us to all of you.


Odds provided by BetMGM Sportsbook


Chicago Bears (+375) at Detroit Lions (-500)

The Lions are big favorites (9.5 points at -110 for both teams). It doesn’t matter who the Lions have played recently, they win big. Six of their last eight wins have been by 10 or more points, and the Bears should change that. Take the Lions and lay 9.5 points (-110).


New York Giants (+150) at Dallas Cowboys (-185)

The Cowboys are solid home favorites (3.5 points at -115 Giants, -105 Cowboys). The Giants are showing indications of going into tank mode, while the Cowboys still have a pulse as the last NFC Wild Card contender. Take the Cowboys and lay 3.5 points (-105).


Miami Dolphins (+150) at Green Bay Packers (-185)

The Packers are modest home favorites (3.5 points at -115 Dolphins, -105 Packers). Miami has a history of playing poorly in cold weather (25°F at kickoff), and the Packers have covered this number in three of their four home wins. The trend continues. Take the Packers and lay 3.5 points (-105).


Las Vegas Raiders (+525) at Kansas City Chiefs (-750)

The Over/Under is low (42.5 points at -110 for both Over and Under). The Chiefs are 13-point favorites – a number you don’t like betting on. The Raiders have struggled to score points, and the Chiefs struggle to cover big spreads, because they don’t blow teams out. Take Under 42.5 points (-110).


Los Angeles Chargers (-130) at Atlanta Falcons (+110)

The Falcons are 2-point home underdogs, but they’re coming off their bye week as the Chargers are coming off a short week of practice after playing Monday night. In a competitive league, that additional healing time is critical. Take the Falcons on the moneyline (-110).


Pittsburgh Steelers (+130) at Cincinnati Bengals (-155)

The Bengals are standard home favorites (3 points at -115 Steelers, -105 Bengals). Pittsburgh plays tight, low-scoring games. Despite the Bengals coming off their bye week, this should be a one-score game, so getting three points is a lot. Take the Steelers plus three points (-115).


Arizona Cardinals (+155) at Minnesota Vikings (-190)

The Over/Under is middle of the road (45 points at -110 for both). The Vikings have scored 20 or more points in all but one game, and the Cardinals have scored 28 or more points in three of their last four games. Both teams have the aerial firepower to top this number. Take Over 45 points (-110).


Indianapolis Colts (-150) at New England Patriots (+125)

The Colts are small road favorites (2.5 points at -120 Colts, +100 Patriots). The Colts have underachieved, but their losses have come against teams better them. New England doesn’t qualify by that standard. Take the Colts and lay 2.5 points (-120).


Seattle Seahawks (-130) at New York Jets (-110)

The Seahawks are road favorites (2 points at -110 for both). The Jets have been a dumpster fire but have the personnel to be good, especially at home with a team traveling across the country to play them. Take the Jets plus 2 points (-110).


Tennessee Titans (+220) at Washington Commanders (-275)

The Commanders are big favorites (6 points at -110 for both teams). Seven of the Titans eight losses have been by seven points or more and look to be the perfect recipe for Washington to end its three-game losing streak. Take the Commanders and lay 6 points (-110).


Houston Texans (-225) at Jacksonville Jaguars (+180)

The Texans are road favorites (4.5 points at -110 for both teams). The Jaguars are coming off their bye and getting players healed up. The Texans won by four points when they met in Houston. The Texans should win, but don’t deserve to be laying that many points on the road. Take the Jaguars plus 4.5 points (-110).


Los Angeles Rams (-150) at New Orleans Saints (+125)

The Rams are small road favorites (2.5 points at -115 Rams, -105 Saints). The Saints have won two straight and are at home, but the Rams are known to make a push late in the season. This a game they need to control and have the ability to do so. Take the Rams and lay 2.5 points (-115).


Tampa Bay Buccaneers (-275) at Carolina Panthers (+125)

The Buccaneers are strong road favorites (6 points at -110 for both teams). Seven of Carolina’s eight losses have been by 10 or more points. The Panthers have shown improvement, but the Buccaneers have won the last three meetings and stymied the Panthers offense. Take the Buccaneers and lay 6 points (-110).


Philadelphia Eagles (+130) at Baltimore Ravens (-155)

This is the highest O/U of the week (51.5 points at -110 for both). These are two legitimate Super Bowl contenders because of their prolific offensive capabilities. Both teams are capable of putting up 30 points. Take Over 51.5 points (-110).


San Francisco 49ers (+260) at Buffalo Bills (-350)

The Bills are huge favorites (7 points at -115 49ers, -105 Bills). This line is based on uncertainty as to whether Brock Purdy, Trent Williams or Nick Bosa will play. If they do, this line will revert downward. Get in now. Take the 49ers plus 7 points (-115).


Cleveland Browns (+200) at Denver Broncos (-250)

The Broncos are strong favorites (5.5 points at -110 for both teams). The Browns just don’t score points – hoisting 18 or fewer points in nine of 11 games. Denver has one of the best defenses in the league, so it won’t take a lot for Bo Nix and the offense to do enough to beat this number. Take the Broncos and lay 5.5 points (-110).