SportsbookWire’s NFL Week 10 picks: ML, ATS and O/U predictions for all games

The SportsbookWire staff makes their NFL Week 10 picks and predictions for moneylines, spreads and totals.

Before looking at SportsbookWire staff’s Week 10 NFL picks, here are the against-the-spread (ATS) and Over/Under (O/U) leaders, according to Teamrankings.com.

At 7-1 ATS, the Detroit Lions (7-1 straight up) feature the NFL’s top ATS record heading into Week 10. They play at the Houston Texans (6-3 SU, 3-5-1 ATS) in the Sunday Night Football game (8:20 p.m. ET / NBC). As of Thursday at 7:31 a.m. ET, BetMGM Sportsbook lists Detroit as 3.5-point favorites.

The Washington Commanders have the next best ATS record at 7-1-1, while the Indianapolis Colts are 7-2 ATS.

On the other side of the spectrum are the Tennessee Titans, who have been the top team to fade — bet against — at 1-7 ATS. Not far behind are the Carolina Panthers (2-7 ATS), the Dallas Cowboys and Miami Dolphins (both 2-6 ATS) and the Seattle Seahawks (2-6-1 ATS).

The Baltimore Ravens are the top Over team at 8-1, while the Panthers and Tampa Bay Buccaneers are both 7-2 O/U.

The LA Chargers improved their top Under mark to 1-7 after a 27-10 win at the Cleveland Browns with an O/U line of 42. The Texans are the next best Under team at 2-7.

Four teams have byes this week. They are the Browns, Green Bay Packers, Las Vegas Raiders and Seahawks.

NFL Week 10 staff picks

Odds provided by BetMGM Sportsbook; access USA TODAY Sports Scores and Sports Betting Odds hub for a full list of NFL odds and check out more NFL expert picks and predictions from SportsbookWire.com.

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