Detroit Pistons at Cleveland Cavaliers odds, picks and predictions

Analyzing Friday’s Detroit Pistons at Cleveland Cavaliers odds and lines, with NBA expert picks, predictions and best bets.

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The Detroit Pistons (0-1) visit the Cleveland Cavaliers (1-0) Friday. Tip-off from Rocket Mortgage FieldHouse is scheduled for 7:30 p.m. ET. Let’s analyze BetMGM Sportsbook’s NBA odds around the Pistons vs. Cavaliers odds and make our expert NBA picks and predictions for the best bets.

Season series: First meeting; Cavaliers won 4-0 last season

Detroit dropped its season opener with a 115-109 loss against the Indiana Pacers Wednesday while failing to cover as a 5.5-point home underdog. G Cade Cunningham scored a game-high 28 points while C Jalen Duren (13 points, 13 rebounds) added a double-double. The Pistons shot 43.2% from the field in the loss.

Cleveland thrashed the Toronto Raptors 136-106 in its Wednesday opener to cover as a 6.5-point road favorite. F Evan Mobley scored a game-high 25 points with 9 rebounds while the Cavs shot 58.6% from the field in the win.

Pistons at Cavaliers odds

Provided by BetMGM Sportsbook; access USA TODAY Sports Scores and Sports Betting Odds hub for a full list of NBA odds. Lines last updated at 10 a.m. ET.

  • Moneyline (ML): Pistons +425 (bet $100 to win $425) | Cavaliers -600 (bet $600 to win $100)
  • Against the spread (ATS): Pistons +10.5 (-105) | Cavaliers -10.5 (-115)
  • Over/Under (O/U): 227.5 (O: -115 | U: -105)

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Pistons at Cavaliers key injuries

Pistons

  • Ausar Thompson (conditioning) out

Cavaliers

  • Max Strus (ankle) out

For most recent updates: Official NBA injury report.

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Pistons at Cavaliers picks and predictions

Prediction

Cavaliers 123, Pistons 109

Moneyline

PASS.

There is no value on the Cavaliers (-600) to win Friday.

Against the spread

LEAN CAVALIERS -10.5 (-115).

Cleveland is going to be a top team in the Eastern Conference this season, while Detroit will most likely be at the bottom. While Cunningham is a dominant player for the Pistons, he will not be able to keep this game within reach by himself and will also face issues against Mobley. Cleveland is a far more rounded team and will be able to rally behind the home crowd to easily handle the Pistons.

Over/Under

BET OVER 227.5 (-115).

The Cavs put up 136 points in their season opener with 6 players scoring at least 11. While their shooting performance was spectacular, it should not be expected to be replicated each night. At home, against a Pistons team that has had its struggles on the defensive side, expect Cleveland to carry a majority of the load to the Over.

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