First look: Ole Miss at South Carolina odds and lines

Looking at Saturday’s Ole Miss at South Carolina college football odds, lines and trends. Here’s what you need to know.

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The Ole Miss Rebels (4-1, 0-1 SEC) meet the South Carolina Gamecocks (3-1, 1-1) in Columbia Saturday. Kickoff at Williams-Brice Stadium is set for 3:30 p.m. ET (ESPN). Below, we look at Ole Miss vs. South Carolina odds from BetMGM Sportsbook’s college football odds before making our expert college football picks and predictions later in the week.

Mississippi dropped from 5th to No. 11 in the US LBM Coaches Poll following Saturday’s 20-17 home loss as a 15.5-point favorite to unranked Kentucky. It was only Ole Miss’ 2nd defeat since Sept. 30,  2023. The Rebels led the Wildcats 17-13 with 10 seconds to go in the 3rd quarter, but they didn’t score again, and UK manufactured a 6-play, 83-yard drive for the eventual winning touchdown with 2:25 remaining. The Rebels were undone by the Wildcats controlling the football for 39 minutes and 43 seconds, while Ole Miss’ time of possession was 20 minutes and 17 seconds.

South Carolina should be rested after enjoying a bye week. The Gamecocks likely needed it as they’re set to open a tough stretch of their schedule with consecutive games against Ole Miss, No. 2 Alabama, No. 17 Oklahoma and No. 21 Texas A&M. The Gamecocks defeated Akron 50-7 as 24.5-point home favorites in their last outing (Sept. 21).

– Rankings: US LBM Coaches Poll, conducted by the American Football Coaches Association and USA TODAY Sports

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Ole Miss at South Carolina odds

Provided by BetMGM Sportsbook; access USA TODAY Sports Scores and Sports Betting Odds hub for a full list of college football odds. Lines last updated Monday at 9:47 a.m. ET.

  • Moneyline: Off the board
  • Against the spread (ATS): Ole Miss -9 (-110) | South Carolina +9 (-110)
  • Over/Under (O/U): 51.5 (O: -115 | U: -105)

FanDuel Sportsbook lists a ML of:

  • Ole Miss -335 (bet $335 to win $100)
  • South Carolina +265 (bet $100 to win $265)

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2024 betting stats

  • ML: Ole Miss 4-1 | South Carolina 3-1
  • ATS: Ole Miss 4-1 | South Carolina 3-1
  • O/U: Ole Miss 1-4 | South Carolina 2-2

Ole Miss vs. South Carolina head-to-head

The gridiron between these 2 programs dates back to 1947 with Ole Miss holding a slight 9-8 edge.

The Rebels and Gamecocks let met in 2020 when Ole Miss snapped a 3-game losing streak to USC with a 59-42 triumph in Oxford. In the last 4 meetings, South Carolina is 3-1 straight up and 3-1 ATS.

As for the total, the Over is 5-1 in the last 6 contests.

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