The Indianapolis Colts (2-2) and Tennessee Titans (2-2) are preparing for what is expected to be a physical matchup in Week 5 at Lucas Oil Stadium.
While this will be the Colts’ third division game thus far in the young season, the Titans are playing in their first matchup against an AFC South opponent in 2023.
Vegas has the Colts sitting as 2.5-point underdogs at home in this matchup, according to BetMGM.
Here’s how the experts around the league see this matchup shaking out:
| Expert | Pick | Score (if applicable) | Link |
| Nate Davis (USA TODAY) | Colts | 23-20 | Link |
| Jarrett Bell (USA TODAY) | Titans | 21-19 | Link |
| Lorenzo Reyes (USA TODAY) | Titans | 19-16 | Link |
| Mike Clay (ESPN) | Colts | — | Link |
| Dan Graziano (ESPN) | Colts | — | Link |
| NFL Network | Titans | 19-18 | Link |
| Bill Bender (Sporting News) | Titans | 22-18 | Link |
| Pete Prisco (CBS Sports) | Titans | 24-20 | Link |
| Cam DaSilva (Sportsbook Wire) | Colts | — | Link |
| Bleacher Report | Colts | 26-23 | Link |
Over at Tallysight, 60% of the analysts have the Colts walking away with a home victory. In terms of the 2.5-point spread, 57% of analysts believe the Colts will cover.
This should be a physical matchup. It always is with the Mike Vrabel-led Titans. It will be an interesting matchup considering how well the Titans play against the run, but it would be a huge boost if the Colts got Jonathan Taylor back from the PUP list.
The Colts matchup well through the air against a shaky Titans secondary so it will be interesting to see how that impacts the game plan.
Regardless, this game is expected to come down to the wire, and the outcome likely will have a big impact down the road.
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