The contest took place at Doug Kingsmore Stadium in Clemson, South Carolina.
Tennessee will next play Clemson on Saturday at 6 p.m. EDT. ESPN2 will televise the matchup.
No. 1 seed Clemson is the host school for the regional. The Tigers defeated Lipscomb, 12-5, on Friday.
PHOTOS: Tennessee baseball wins NCAA Tournament game versus Charlotte
PHOTOS: A look at Tony Vitello through the years
Following Tennessee’s win versus Charlotte on Friday in the NCAA Tournament, sixth-year Vols’ head coach Tony Vitello met with media. Vitello and Tennessee’s student-athlete media availability can be watched below.