San Antonio Spurs at Los Angeles Lakers odds, picks and predictions

Analyzing Wednesday’s San Antonio Spurs at Los Angeles Lakers odds and lines, with NBA expert picks, predictions and best bets.

The San Antonio Spurs (14-33) and Los Angeles Lakers (22-26) meet Wednesday at Crypto.com Arena. Tip-off is scheduled for 10:30 p.m. ET. Below, we analyze Tipico Sportsbook’s lines around the Spurs vs. Lakers odds, and make our expert NBA picks and predictions.

The Spurs failed to cover the spread as 8-point underdogs Monday in a 147-127 loss at the Portland Trail Blazers. F Keldon Johnson scored a team-high 20 points as San Antonio lost for the 7th time in 8 games. The Spurs are 6-4 against the spread (ATS) in their last 10 games after losing by 20 or more points in their previous contest.

The Lakers failed to cover as 4.5-point underdogs Tuesday in a 133-115 loss vs. the Los Angeles Clippers. F LeBron James finished with 46 points and 9 made 3-pointers, both game-highs, as the Lakers failed to capitalize after winning back-to-back games, sitting 13th in the Western Conference. The Lakers are 14-2 ATS in their last 16 games vs. teams with a losing record.

Anthony Davis (foot) is expected to return to the lineup Wednesday after missing 20 games and newly acquired F Rui Hachimura will reportedly be available to play.

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Spurs at Lakers odds

Provided by Tipico Sportsbook; access USA TODAY Sports Scores and Sports Betting Odds hub for a full list. Lines last updated at 3:25 p.m. ET.

  • Moneyline (ML): Spurs +210 (bet $100 to win $210) | Lakers -250 (bet $250 to win $100)
  • Against the spread (ATS): Spurs +6.5 (-108) | Lakers -6.5 (-112)
  • Over/Under (O/U): 243.5 (O: -110 | U: -110)

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Spurs at Lakers key injuries

Spurs

  • Romeo Langford (hip) questionable
  • Devin Vassell (knee) out

Lakers

  • Not yet submitted

For most recent updates: Official NBA injury report.

Spurs at Lakers picks and predictions

Prediction

Lakers 130, Spurs 119

Moneyline

PASS.

The Lakers (-250) should win, but there is no need to risk more than 2 times your potential profit on the moneyline when Los Angeles should win by margin. Bet the spread or total instead.

Against the spread

BET LAKERS -6.5 (-112).

Stars returning from injury can sometimes disrupt team chemistry, but Davis is familiar enough with the Lakers that the 8-time All-Star should instantly make Los Angeles better. The league saw a similar situation last Wednesday when G Bradley Beal returned to Washington and the Wizards guard has since led his team to 3 straight wins and covers. Los Angeles is 3-0 ATS vs. the Spurs this season and the addition of Davis should help the Lakers cover for a 4th consecutive meeting. Lay the points.

Over/Under

BET OVER 243.5 (-110).

The Over is 8-0-1 in San Antonio’s last 9 road games vs. teams with a winning record at home and 7-1 in Los Angeles’ last 8 games following a loss by more than 10 points in their previous contest. These teams play high-scoring games vs. each other in Los Angeles as the Over is 9-3-1 in the last 13 meetings and Wednesday’s matchup should be another high-scoring affair.

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