The Arizona Cardinals (1-2) and the Carolina Panthers (1-2) meet Sunday at Bank of America Stadium in Charlotte, N.C. Kickoff is scheduled for 4:05 p.m. ET (FOX). Below, we analyze Tipico Sportsbook‘s lines around the Cardinals vs. Panthers odds, and make our expert NFL picks and predictions.
The Cardinals have been very Jekyll and Hyde to date. They were pounded 44-21 in Week 1 against the Kansas City Chiefs, won 29-23 at the Las Vegas Raiders in OT in Week 2, and then lost 20-12 against the Los Angeles Rams in Week 3.
The Panthers lost 26-24 at home in Week 1 to the Cleveland Browns. After a 19-16 loss at N.Y. Giants in Week 2, Carolina found success at home against the New Orleans Saints last week, winning 22-14.
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Cardinals at Panthers odds
Provided by Tipico Sportsbook; access USA TODAY Sports Scores and Sports Betting Odds hub for a full list. Lines last updated at 1:12 a.m. ET.
- Moneyline (ML): Cardinals -103 (bet $103 to win $100) | Panthers -115 (bet $115 to win $100)
- Against the spread (ATS): Cardinals +1.5 (-115) | Panthers -1.5 (-107)
- Over/Under (O/U): 43.5 (O: -112 | U: -108)
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Cardinals at Panthers key injuries
Cardinals
- WR Marquis Brown (foot) questionable
- WR A.J. Green (knee) out
- PK Matt Prater (hip) questionable
- DE J.J. Watt (calf) questionable
Panthers
- DE Marquis Haynes (knee) questionable
- RB Christian McCaffrey (thigh) questionable
- WR Laviska Shenault Jr. (hamstring) questionable
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Cardinals at Panthers picks and predictions
Prediction
Cardinals 27, Panthers 20
Moneyline
The CARDINALS (-103) are the play in this road game. The Panthers (-115) could potentially be without McCaffrey, but even if he plays, he hasn’t been a difference maker so far for Carolina. This team is still very middling.
QB Kyler Murray should find plenty of room to operate in Sunday’s game, as the Panthers rank 22nd against the run, and 18th in the NFL in total yards allowed (348.7). Look for Murray to be a difference maker.
Against the spread
CARDINALS +1.5 (-107) doesn’t really make sense, paying slightly more than the money line. Unless you are feeling a tie or 1-point game will happen, just play the ML.
And if you like the tie, then you like the Game To Go To Overtime (+900). Play that lightly instead. I don’t like it, though.
Over/Under
OVER 43.5 (-112) is the best play on the board.
Arizona is going to be able to move the ball up and down the field on this defense. On the other side, even the ineffective QB Baker Mayfield should find plenty of open spaces against a Cardinals defense which ranks 30th in the NFL against the pass, allowing 281.0 yards per game, while coughing up 29.0 PPG. It’s not or never for the Bake Show in Charlotte.
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