The Chicago Bears open the 2022 NFL regular season against an opponent that was on the doorstep of playing in Super Bowl LVI in the San Francisco 49ers.
Coming off a 10-7 season, the 49ers are loaded yet again with a playoff-caliber roster and are looking to start the season off on a positive note. They do have some notable changes, however, that are worth watching, including their quarterback swap.
But there’s more players on the 49ers to watch than just the quarterback, although all eyes are going to be on that situation all season long. Here are six key opponents to watch when the Bears and 49ers meet up on the lakefront this Sunday.