The Houston Astros (75-43) try to turn it around against the Chicago White Sox (61-56) Wednesday in the 3rd game of a 4-game set at Guaranteed Rate Field. First pitch is set for 8:10 p.m. ET. Let’s analyze Tipico Sportsbook‘s lines around the Astros vs. White Sox odds with MLB picks and predictions.
Season series: White Sox lead 3-2
The Astros blew leads late in the last 2 games to fall to the White Sox 4-2 Monday and 4-3 Tuesday. Houston is just 11-9 over the last 20 games in this rough patch.
The White Sox are playing spirited baseball, having won 5 in a row. They’re 1 game back of the AL Central-leading Guardians. Chicago is doing it with starting pitching from unlikely sources like 8 strong innings from RHP Johnny Cueto Monday.
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Astros at White Sox projected starters
LHP Framber Valdez vs. RHP Michael Kopech
Valdez (11-4, 2.73 ERA) makes his 23rd start. He has a 1.13 WHIP, 3.1 BB/9 and 8.1 K/9 in 142 IP.
- Having career year, tied for lowest HR/9 in MLB at 0.4
- Last start: Allowed 4 H and 1 BB in 7 shutout IP with 8 K in 7-3 home win vs. Texas Thursday
- Allowed 3 ER on 8 H and no BB with 7 K over 6 IP in 13-3 home win vs. White Sox June 17
Kopech (4-8, 3.18 ERA) makes his 22nd start. He has a 1.18 WHIP, 4.4 BB/9 and 8.3 K/9 in 104 2/3 IP.
- Coming off his best start of career with 6 shutout IP and 11 K in a no-decision, White Sox 2-0 victory vs. Detroit Friday
- Allowed 4 ER on 7 H and 1 BB with 4 K in 5 IP in a 4-3 loss at Astros June 19
Astros at White Sox odds and lines
Odds provided by Tipico Sportsbook; access USA TODAY Sports Scores and Sports Betting Odds hub for a full list. Lines last updated at 2 p.m. ET.
- Money line (ML): Astros -155 (bet $155 to win $100) | White Sox +125 (bet $100 to win $125)
- Run line (RL)/Against the spread (ATS): Astros -1.5 (+110) | White Sox +1.5 (-135)
- Over/Under (O/U): 7.5 (O: -130 | U: +105)
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Astros at White Sox picks and predictions
Prediction
Astros 6, White Sox 4
Money line
The Astros are the superior team, and now that they have blown leads late in the last 2 games, I look for them to respond. White Sox starter Kopech has an electric fastball, but he can’t locate his stuff. His walk rate is far too high, which gets him into trouble, and the Astros feast on fastballs.
HOUSTON (-155) feels like a bargain.
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Run line/Against the spread
PASS. We’re picking the Astros to win by 2 runs, but the ML is a good enough value to be happy with and not get overzealous.
Over/Under
This is the first contending team Kopech has faced in 5 starts, and I look for Houston to get on the board early. The Over is 5-2-1 in the last 8 meetings between these teams. The forecast calls for a wind blowing out to right-center field at 9 mph. The Over is also 4-0 in Valdez’s last 4 starts. Take the OVER 7.5 (-130) for a FULL UNIT.
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