The Toronto Blue Jays (54-43) host the St. Louis Cardinals (51-47) Wednesday for the 2nd game of their interleague back-to-back set at Rogers Centre. First pitch is set for 7:07 p.m. ET. Let’s analyze Tipico Sportsbook‘s lines around the Cardinals vs. Blue Jays odds with MLB picks and predictions.
Toronto clobbered St. Louis 10-3 Wednesday with the Blue Jays’ top of the order (CF George Springer, 1B Vladimir Guerrero Jr. and C Alejandro Kirk) combining for 3 home runs with 7 RBIs including Springer’s 6th-inning grand slam.
Season series: Toronto leads 2-1 and has a plus-10 run differential in those meetings.
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Cardinals at Blue Jays projected starters
RHP Adam Wainwright vs. RHP Kevin Gausman
Wainwright is 6-8 with a 3.40 ERA, 1.24 WHIP, 2.6 BB/9 and 7.0 K/9 in 116 1/3 IP across 19 starts.
- Last start: Loss, 9-5, Friday at the Cincinnati Reds with 5 1/3 IP, 7 ER, 5 H, 2 HR, 3 BB and 2 K.
- 2022 road splits: 3-5 with a 4.81 ERA (58 IP, 31 ER), 1.40 WHIP, 9 HR and 6.2 K/9 in 10 starts.
Gausman is 7-7 with a 3.00 ERA, 1.29 WHIP, 1.6 BB/9 and 10.5 K/9 in 99 IP over 18 starts.
- Last start: Win, 28-5, Friday at the Boston Red Sox with 5 IP, 3 ER, 7 H, 2 HR, 0 BB and 10 K.
- 2022 vs. the Cardinals: 1 start — an 8-1 win May 24 in St. Louis — with 6-scoreless IP, 4 H, 2 BB and 8 K.
Cardinals at Blue Jays odds and lines
Odds provided by Tipico Sportsbook; access USA TODAY Sports Scores and Sports Betting Odds hub for a full list. Lines last updated at 2:39 p.m. ET.
- Money line (ML): Cardinals +230 (bet $100 to win $230) | Blue Jays -300 (bet $300 to win $100)
- Run line (RL)/Against the spread (ATS): Cardinals +1.5 (+102) | Blue Jays -1.5 (-125)
- Over/Under (O/U): 7.5 (O: -130 | U: +105)
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Cardinals at Blue Jays picks and predictions
Prediction
Blue Jays 7, Cardinals 4
Money line
PASS.
I’m not risking more than 2 times my potential return for any MLB regular-season ML favorite let alone against a Cardinals team that has enough talent despite the absence of both of its All-Stars — 3B Nolan Arenado and 1B Paul Goldschmidt — who aren’t vaccinated for COVID and can’t travel to Canada.
That said, the Blue Jays are the right side of this bet because they are 29-17 straight up (SU) as home favorites and 45-31 SU vs. right-handed starters. While the Cardinals are 11-20 SU as road underdogs and 40-38 SU against righty starters.
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Run line/Against the spread
BET a HALF-UNIT on the BLUE JAYS -1.5 (-125) because their RL opened at -115 and has been steamed up for obvious reasons by sharp action according to Pregame.com.
Gausman leads MLB in FIP (1.98) and Toronto’s lineup is much more productive vs. right-handed pitching. However, the Blue Jays are just 17-29 RL as home favorites and I hate paying a tax for a RL.
Over/Under
BET a HALF-UNIT on the OVER 7.5 (-130) because Toronto is 27-19 O/U as a home favorite, Cardinals-Blue Jays have a combined 18-9 O/U record in interleague play and Rogers Centre is hitter-friendly with the 10th-highest park factor.
My hesitancy with the OVER 7.5 (-130) is most of the market is hammering the Over as well and St. Louis’s is without its 2 best sluggers.
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