The Cleveland Guardians (40-39) and the Detroit Tigers (33-47) wrap up a 4-game series on Wednesday at Comerica Park in Detroit. First pitch is scheduled for 1:10 p.m. ET. Let’s analyze Tipico Sportsbook‘s lines around the Guardians vs. Tigers odds with MLB picks and predictions.
Season series: Tigers lead series 6-2, and they’re 5-1 in Detroit.
The Guardians look to salvage at least 1 win out of this 4-game set at Comerica. Cleveland lost 11-4 in Tuesday’s game, the first Over in 5 outings.
The Tigers seek to equal a season-high 4-game win streak. Detroit has outscored Cleveland 20-8 in the first 3 games of this series.
Guardians at Tigers projected starters
RHP Shane Bieber vs. RHP Michael Pineda
Bieber (3-4, 3.16 ERA) makes his 16th start. He has a 1.16 WHIP, 2.2 BB/9 and 9.2 K/9 through 91 IP.
- Is 1-1 with a 1.80 ERA with 15 K through 15 IP across 2 starts vs. DET this season.
- Has posted a 2-1 record, 2.51 ERA and .242 opponent batting average in 57 1/3 IP over 9 road starts.
Pineda (1-3, 3.62 ERA) makes his 7th start. He has a 1.13 WHIP, 1.3 BB/9 and 4.9 K/9 through 27 1/3 IP.
- Has posted a 1-2 record, 2.82 ERA and .238 OBA with 13 K across 22 1/3 IP in 5 home outings.
- Faced Cleveland last Sept. 6, 2021 as a member of the New York Yankees, allowing 2 H and 1 BB across 3 scoreless IP of relief.
Guardians at Tigers odds and lines
Odds provided by Tipico Sportsbook; access USA TODAY Sports Scores and Sports Betting Odds hub for a full list. Lines last updated at 7:40 a.m. ET.
- Money line (ML): Guardians -190 (bet $190 to win $100) | Tigers +155 (bet $100 to win $155)
- Run line (RL)/Against the spread (ATS): Guardians -1.5 (-108) | Tigers +1.5 (-112)
- Over/Under (O/U): 7.5 (O: -125 | U: +100)
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Guardians at Tigers picks and predictions
Prediction
Tigers 4, Guardians 3
Money line
The TIGERS (+155) look to finish off the 4-game series sweep, and they’re a tremendous value at this price based on how they’re playing.
The Guardians (-190) are just too expensive to trust, even if their best pitcher is on the bump.
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Run line/Against the spread
The TIGERS +1.5 (-112) are worth playing on the run line if you just don’t trust them to close out the Guardians -1.5 (-108) for the four-game sweep.
Detroit has won each of the first 3 games in this series by at least 2 runs, therefore the alternate line of TIGERS -1.5 (+275) is worth a roll of the dice.
Over/Under
The UNDER 7.5 (+100) is the lean here, although it’s going to be super close.
The Under is 5-2-1 in the previous 8 meetings in this series and 3-1-1 in the past 5 meetings in the Motor City. The Under is also 7-3-2 in the past 12 road games for Cleveland and 7-1-2 in the past 10 against winning teams for Detroit.
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