Chicago White Sox at Minnesota Twins odds, picks and predictions

Analyzing Friday’s Chicago White Sox at Minnesota Twins odds and lines, with MLB expert picks and predictions.

The Chicago White Sox (6-6) meet the Minnesota Twins (5-8) Friday for the opener of a 3-game series at Target Field. First pitch is scheduled for 8:10 p.m. ET. Let’s analyze Tipico Sportsbook‘s lines around the White Sox vs. Twins odds with MLB picks and predictions.

Chicago has lost 4 consecutive games, recently being swept 3-0 at the Cleveland Guardians Wednesday (doubleheader) and Thursday.

Minnesota prevented a 3-game sweep Wednesday by beating the Royals 1-0 in Kansas City following a 2-2 split of a 4-game series at the Boston Red Sox.

The White Sox won last year’s regular-season series with the Twins 13-6, outscoring Minnesota 123-71.

White Sox at Twins: Projected starters

RHP Michael Kopech vs. RHP Bailey Ober 

Kopech (0-0, 1.00 ERA) has 2 no-decisions to start 2022, first throwing 4 IP with 1 ER in a 10-1 win at the Detroit Tigers April 10, then going 5 IP with 0 ER in a 3-2 win over the Tampa Bay Rays Saturday.

  • Career vs. Twins: 1-0 with a 1.29 ERA (7 IP, 1 ER), 6 H, 3 BB and 8 K over 4 relief appearances and 1 start

Ober (1-1, 3.27 ERA) lost at the Red Sox 8-1 Sunday, working 6 IP with 0 ER, 4 H, 1 BB and 3 K.

  • 2021 vs. White Sox: 1-1 with a 4.76 ERA (22 2/3 IP, 12 ER), 1.32 WHIP and 9.5 K/9 across 5 starts in his rookie season
  • vs. White Sox on the current roster: 4.33 FIP with a .224 batting average, .312 wOBA, .460 expected-slugging percentage (xSLG), 27.4 K% and 93.3 mph exit velocity (EV) in 62 plate appearances.

White Sox at Twins odds and lines

Odds provided by Tipico Sportsbook; access USA TODAY Sports Scores and Sports Betting Odds hub for a full list. Lines last updated at 1:36 p.m. ET.

  • Money line (ML): White Sox -108 (bet $108 to win $100) | Twins -112 (bet $112 to win $100)
  • Run line (RL)/Against the spread (ATS): White Sox -1.5 (+155) | Twins +1.5 (-190)
  • Over/Under (O/U): 7.5 (O: -112 | U: -108)

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White Sox at Twins picks and predictions

Prediction

White Sox 4, Twins 2

Money line

LEAN WHITE SOX (-108).

They’ve been steamed from slight underdogs on the opener up to the current price and they have a significant edge in the pitching matchup.

Ober grades in the 22nd percentile or worse in xSLG, EV, hard-hit rate, barrel rate and expected wOBA, according to Statcast.

Also, the White Sox’s bullpen is 6th in FIP and 7th in home runs allowed per 9 innings, per FanGraphs. Minnesota’s bullpen ranks 28th in both of those respective categories.

However, it’s only a LEAN WHITE SOX (-108) because the Under is my favorite wager in this contest.

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Run line/Against the spread

PASS.

I’m not confident enough in Chicago to sprinkle on White Sox -1.5 (+155). Chicago is 38-44 on the RL versus AL Central foes since the beginning of last season; Minnesota owns a 32-47 RL record vs. the division over that span.

Over/Under

BET UNDER 7.5 (-108) for 1 unit.

Chicago’s lineup has the second-worst wOBA and wRC+ versus right-handed pitching. Minnesota’s lineup is 21st in wRC+ and 23rd in wOBA.

Minnesota is 0-5 O/U in the last 5 games versus a righty starter, the Under has cashed in 4 of the past 5 White Sox-Twins meetings and the total has been lowered from 8.5 on the opener by sharp-line movement, according to Pregame.com.

On top of that, the weather forecast is predicting higher than 15 mph winds blowing in from right-center field.

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