The Iowa State Cyclones (6-4, 4-3 Big 12) visit the No. 11 Oklahoma Sooners (9-1, 6-1 Big 12) Saturday at Memorial Stadium in Norman. Kickoff is scheduled for noon ET. Below, we look at the Iowa State vs. Oklahoma odds and lines, and make our expert college football picks, predictions and bets.
Things have gone off the rails a bit for Iowa State, losing two of the past three, and going 1-3 ATS in the previous four outings. The defense was trampled at Texas Tech in a 41-38 loss in Lubbock last Saturday.
The Sooners fell at Baylor 27-14 last week as 4-point favorites. The Sooners enter this game just 1-2 ATS across the past three, and 4-6 ATS on the season.
Rankings courtesy of the AFCA Coaches Poll powered by USA TODAY Sports.
Iowa State at Oklahoma odds, spread and lines
Odds provided by Tipico Sportsbook; access USA TODAY Sports Scores and Odds for a full list. Lines last updated Thursday at 6:42 a.m. ET.
- Money line: Iowa State +140 (bet $100 to win $140) | Oklahoma -175 (bet $175 to win $100)
- Against the spread (ATS): Iowa State +3.5 (-112) | Oklahoma -3.5 (-108)
- Over/Under (O/U): 60.5 (O: -108 | U: -112)
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Iowa State at Oklahoma odds, lines, picks and predictions
Prediction
Oklahoma 41, Iowa State 34
Money line
OKLAHOMA (-175) isn’t a bad play at this price if you just want to forget about laying the points and pick a winner straight up. The Sooners aren’t returning home and losing to Iowa State even though the Cyclones have been a thorn in the side of the Sooners in recent seasons. OU is angry, which is bad news for the visitors.
Against the spread
OKLAHOMA -3.5 (-108) will bounce back after last week’s debacle at Waco, taking out its frustrations on Iowa State.
This game will be a seesaw affair early on, as QB Brock Purdy and the Cyclones offense is potent, and will challenge the favorites. But the Sooners will find a way, and should win this one by at least a touchdown, tapping into last week’s loss for motivation.
Over/Under
The OVER 60.5 (-108) is the best bet on the board in this game. Yes, Oklahoma scored a season-low 14 points last week. It won’t happen again.
Iowa State posted 89 rushing yards and 356 passing yards last week, while allowing 207 yards on the ground and 322 yards through the air. This game is going to be a shootout, and Over bettors might be holding a winning ticket sometime in the third quarter if everything goes according to plan.
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