The Indianapolis Colts (4-5) are back home for the third consecutive game hosting the Jacksonville Jaguars (2-6) at Lucas Oil Stadium in Week 10.
Coming off of a game in which they scored the most points since 2014, the Colts will open Week 10 as massive 10.5-point home favorites over the Jaguars in this first meeting between these the two teams, per Tipico Sportsbook.
| Spread | Moneyline | Total Points | |
| Jacksonville Jaguars (2-6) | +10.5 | +380 | O 47.5 -112 |
| Indianapolis Colts (4-5) | -10.5 | -540 | U 47.5 -108 |
While the Colts are coming off their big win, the Jaguars are coming off of a huge upset over the Buffalo Bills in Week 9. The Bills offense couldn’t get anything going as Jaguars defensive end Josh Allen got the best of Bills quarterback Josh Allen for the majority of the day.
The Colts, meanwhile, are looking to stay in the hunt with three more games until their bye in Week 14. They are right in the thick of the wild-card race and with the Titans pulling away with the division, that seems to be their only hope.
Regardless, the Colts will open this week as massive favorites and should take care of business at home barring a breakout game from rookie Trevor Lawrence.
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