First look: Cleveland Browns at New England Patriots odds and lines

Looking at Sunday’s Cleveland Browns at New England Patriots Week 10 NFL odds, lines and trends. Here’s what you need to know.

The Cleveland Browns (5-4) stop by Gillette Stadium Sunday for a Week 10 meeting with the New England Patriots (5-4) at 1 p.m. ET. Below, we look at the Browns vs. Patriots odds and lines; check back for our NFL picks and predictions.

Cleveland had the most lopsided victory Sunday after pummeling the Cincinnati Bengals 41-16 as a 1.5-point underdog. It was Cleveland’s first game without WR Odell Beckham Jr. as both parties decided to split earlier in the week.

Browns QB Baker Mayfield and the running game stepped up in OBJ’s absence. Mayfield completed 14-for-21 throws for 218 yards and a 2 TD:0 INT ratio. RB Nick Chubb added 137 rushing yards on just 14 carries with 2 TDs.

New England squashed the Carolina Panthers 24-6 Sunday as a 3.5-point road favorite. The Patriots defense held Panthers QB Sam Darnold (16 of 33 pass attempts) to 172 passing yards with 0 touchdowns and 3 interceptions, which included a pick-six from New England CB J.C. Jackson.

Also see: All Week 10 odds and lines

Browns at Patriots odds, spread and lines

Odds provided by Tipico Sportsbook; access USA TODAY Sports’ betting odds for a full list. Lines last updated Monday at 11:57 a.m. ET.

  • Money line: Browns +105 (bet $100 to win $105) | Patriots -130 (bet $130 to win $100)
  • Against the spread (ATS): Browns +2.5, -112 (bet $112 to win $100) | Patriots -2.5, -108 (bet $108 to win $100)
  • Over/Under (O/U): 44.5, O: -115 (bet $115 to win $100) | U: -105 (bet $105 to win $100)

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2021 betting stats:

  • ML: Browns 5-4 | Patriots 5-4
  • ATS: Browns 5-4 | Patriots 5-4
  • O/U: Browns 5-4 | Patriots 4-5

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Browns at Patriots head-to-head

New England handled Cleveland 27-13 as a 9.5-point home favorite the last time these teams met (Week 8 of 2019). However, the Patriots no longer have QB Tom Brady nor their leading rusher and receiver from that game.

The Patriots held Mayfield to 194 passing yards on 20-for-31 passing with a 1 TD:1 INT ratio. Chubb gained 131 rushing yards on 20 carries but failed to get into the end zone.

Since the beginning of last season, the Browns are 6-10 ATS as favorites and the Patriots are 6-5 ATS as underdogs. Last year was New England’s first season without Brady under center and the first year of Cleveland head coach Kevin Stefanski’s Browns’ tenure.

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