The Indiana Hoosiers (2-6, 0-5 Big Ten) and No. 10 Michigan Wolverines (7-1, 4-1) tussle in a Big Ten East Division contest Saturday night in Ann Arbor, Michigan. The game at Michigan Stadium will kick off at 7:30 p.m. ET. Below, we look at the Indiana vs. Michigan odds and lines; check back for our college football picks and predictions.
Rankings according to the AFCA Coaches Poll powered by USA TODAY Sports.
Indiana is coming off a road loss to Maryland and has lost four straight games for the first time since 2018.
The Hoosiers have endured scoring woes for most of the season and now — after a 38-35 setback against the Terrapins — have coughed up 92 points over the last two weeks. IU is 1-3 on the road; all three losses have come in Big Ten play.
The Wolverines return to the Big House after an unsuccessful trip to Spartan Stadium in Saturday’s intrastate battle at then-No. 7 Michigan State.
UM spit the bit on the 30-14 late-third-quarter lead, as coach Jim Harbaugh’s combined record against MSU and Ohio State fell to 3-9.
The Wolverines lost to the Spartans despite outgaining them, 552 yards to 395, and holding MSU to a 4-of-13 mark on third downs.
Indiana at Michigan odds, spread and lines
Odds provided by Tipico Sportsbook; access USA TODAY Sports’ betting odds for a full list. Lines last updated Monday at 11:02 a.m. ET.
- Money line: Indiana +650 (bet $100 to win $650) | Michigan -1100 (bet $1,100 to win $100)
- Against the spread (ATS): Indiana +19.5, -112 (bet $112 to win $100) | Michigan -19.5, -108 (bet $108 to win $100)
- Over/Under (O/U): 50.5, O: -115 (bet $115 to win $100) | U: -105 (bet $105 to win $100)
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2021 betting stats:
- ML: Indiana 2-6 | Michigan 7-1
- ATS: Indiana 2-6 | Michigan 6-2
- O/U: Indiana 3-5 | Michigan 4-4
Indiana at Michigan head-to-head
Michigan is 59-10 across 69 all-time meetings against IU. Among the 10 wins for the Hoosiers is a 38-21 win in Bloomington, Indiana last fall.
Indiana held UM to 357 yards in the game (13 on the ground) and controlled the game wire to wire. The victory was the Hoosiers’ first over Michigan since 1987. Indiana is 4-1-1 ATS over the last six series meetings.
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