The Arizona Cardinals (5-0) are the only undefeated team through five weeks, while the Jacksonville Jaguars and Detroit Lions both failed to pick up their first win and dropped to 0-5. Below, we look at the Week 6 NFL odds and lines; check back for our NFL picks and predictions.
The Cards spoiled San Francisco 49ers QB Trey Lance‘s first NFL start with a 17-10 victory in Week 5. Their unblemished record is put to the test in a road tilt against the Cleveland Browns in Week 6. The first bye weeks of the season are scheduled for Week 6 as the Atlanta Falcons, New Orleans Saints, New York Jets and 49ers have the week off.
Odds provided by Tipico Sportsbook and last updated Monday, Oct. 11
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