The 49ers couldn’t get out of the first quarter against the Eagles without a player exiting because of an injury. Defensive tackle Kevin Givens walked slowly off the field with an ankle issue and is questionable to return.
San Francisco has a little better depth on the interior against the Eagles with Javon Kinlaw’s return, but with DL Zach Kerr inactive it’s still a little thin inside where the 49ers were gashed by the Lions’ run game in Week 1.