The Cleveland Browns and Kansas City Chiefs meet Sunday at Arrowhead Stadium. Kickoff is scheduled for 4:25 p.m. ET and the game is televised on CBS. Below, we look at the Browns at Chiefs odds and lines, and make our best NFL picks, predictions and bets.
The Browns head into this regular-season opener looking to snap an ugly run. They’re 0-15-1 in Week 1 since 2005, and they’re 5-15-1 against the spread in their previous 21 Week 1 games.
The defending AFC champion Chiefs have no such bad luck in Week 1, or otherwise lately. They covered the spread in each of their past four regular-season openers, while going 12-2 ATS in their last 14 games in September.
Also see: 2021 NFL team win totals
Browns at Chiefs odds, spread and lines
Odds provided by Tipico Sportsbook; access USA TODAY Sports’ betting odds for a full list. Lines last updated Saturday at 11:55 a.m. ET.
- Money line: Browns +190 (bet $100 to win $190) | Chiefs -240 (bet $240 to win $100)
- Against the spread (ATS): Browns +5.5 (-110) | Chiefs -5.5 (-110)
- Over/Under (O/U): 54.5 (O: -115 | U: -105)
PLAY: Try our new, free daily Pick’em Challenge and win. Play now!
Browns at Chiefs key injuries
Browns
- WR Odell Beckham Jr. (knee) questionable
- DE Jadeveon Clowney (illness) questionable
- S Grant Delpit (hamstring) questionable
- S Ronnie Harrison Jr. (ankle) questionable
- C JC Tretter (knee) questionable
- PK Chase McLaughlin (hamstring) questionable
Chiefs
- DE Frank Clark (hamstring) questionable
- DT Derrick Nnadi (hip) questionable
- OL Austin Blythe (abdomen) out
WIN YOUR FANTASY FOOTBALL LEAGUE!
For 25 years, TheHuddle.com has been helping fantasy players just like you win. This year, it’s your turn! Custom player rankings, tools and more to give you the edge over your competition.
Use code SBW21 to take 20% OFF a new subscription. Join now!
Browns at Chiefs odds, lines, predictions and picks
Prediction
Chiefs 34, Browns 24
Money line
The Chiefs (-240) will cost you two and a half times your potential return, and that’s a little too much risk despite the fact the Browns have been awful in regular-season openers for over a decade and a half.
AVOID and look to the spread.
Against the spread
CHIEFS -5.5 (-110) is a great play in the regular-season opener in this replay of last season’s AFC Divisional Round playoff game. The public has been all over the Browns, and it’s a bit misguided.
Perhaps some bettors are looking at last season’s 22-17 playoff game near-miss by the Browns in Kansas City, but remember, Chiefs QB Patrick Mahomes was knocked out of that game for a large chunk. Backup QB Chad Henne finished up and the Chiefs still won the game.
This one won’t be nearly as close.
Over/Under
The play is the OVER 54.5 (-115) in this AFC showdown between two Super Bowl hopefuls.
I like the fact the Over is 6-0 in the past six regular-season openers for the Chiefs while they’ve hit the Over in 15 of their last 21 September games, as well.
We have two top-notch quarterbacks and a bevy of impressive skill position players on both sides. The defenses won’t be able to keep up.
Also see: Week 1 staff picks
If you’re looking for more sports betting picks and tips, access all of our content at SportsbookWire.com. Please gamble responsibly.
Follow Joe Williams on Twitter. Follow SportsbookWire on Twitter and like us on Facebook.
Access more NFL coverage:
TheHuddle Fantasy Football | BearsWire | BengalsWire | BillsWire | BroncosWire | BrownsWire | BucsWire | CardsWire | ChargersWire | ChiefsWire | CowboysWire | DolphinsWire | EaglesWire | FalconsWire | GiantsWire | JaguarsWire | JetsWire | LionsWire | NinersWire | PackersWire | PanthersWire | PatriotsWire | RaidersWire | RamsWire | RavensWire | SaintsWire | SeahawksWire | SteelersWire | TexansWire | TitansWire | VikingsWire | WashingtonFootballWire | DraftWire | TouchdownWire | TheListWire
Gannett may earn revenue from audience referrals to betting services. Newsrooms are independent of this relationship and there is no influence on news coverage. This information is for entertainment purposes only. We make no representations or warranties as to the accuracy, completeness, or reliability of any content.
[lawrence-newsletter]
[lawrence-auto-related count=3 category=1367]