WATCH: Cleveland Browns At Kansas City Chiefs, Week 1, Key Facts, Stats

See betting lines, statistical trends and relevant facts for the 2021 NFL season opener between the Cleveland Browns and Kansas City Chiefs.

The Cleveland Browns open this season where the last one ended — on the road against the reigning AFC champion Kansas City Chiefs. The Browns lost that divisional-round playoff game 22-17, with the close margin helping to fuel expectations in Cleveland this season.

The Browns have lost nine consecutive road openers as underdogs, but they also hadn’t made the playoffs since 2002 until last season. They’re underdogs again in this one. Go to Tipico Sportsbook for the most updated odds.

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