Seattle Mariners at Houston Astros odds, expert picks and prediction

Analyzing Monday’s Seattle Mariners at Houston Astros odds and lines, with MLB expert picks and predictions.

The Seattle Mariners (75-62) and Houston Astros (79-57) play the opener of a three-game series Monday at Minute Maid Park. First pitch is scheduled for 7:10 p.m. ET. Let’s analyze the lines around the Mariners vs. Astros odds with MLB picks and predictions.

Mariners LHP Yusei Kikuchi (7-7, 4.12 ERA) makes his 26th start. He has a 1.23 WHIP, 9.3 K/9 and 3.3 BB/9 through 144 1/3 IP.

  • Twirled 7 scoreless frames with 4 hits and 2 walks allowed in a no-decision against the Astros Tuesday.
  • Was hammered for 7 runs on 7 hits and 3 homers in just 2 2/3 IP in a loss Aug. 20 at Houston.

Astros RHP Lance McCullers Jr. (10-4, 3.20 ERA) makes his 24th start. He has a 1.25 WHIP, 10.5 K/9 and 4.3 BB/9 through 132 1/3 IP.

  • Allowed just 4 hits and 3 walks across 5 scoreless innings in a no-decision in Seattle Tuesday.
  • Allowed just 2 runs on 5 hits and a walk with 8 strikeouts over 6 innings in a win against the Mariners Aug. 20, also opposite Kikuchi.

Mariners at Astros odds, lines, picks and prediction

MLB odds provided by Tipico Sportsbook; access USA TODAY Sports for a full list. Odds last updated at 9:55 a.m. ET.

  • Money line: Mariners +175 (bet $100 to win $175) | Astros -220 (bet $220 to win $100)
  • Against the spread/ATS: Mariners +1.5 (-117) | Astros -1.5 (-103)
  • Over/Under: 8.5 (O: -115 | U: -107)

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Prediction

Astros 6, Mariners 3

Money line (ML)

The Astros (-220) will cost you more than two times your potential return and that’s a bit too expensive.

AVOID and look to the spread instead.

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Run line/Against the spread (ATS)

ASTROS -1.5 (-103) are a much better play at near even money on the run line. Houston took two of three from Seattle from Aug. 20-22, and they won the first two games by a combined score of 27-4. One of those games was a 12-3 win Aug. 20 with McCullers on the hill against Kikuchi.

Over/Under (O/U)

OVER 8.5 (-110) is worth a small-unit play.

The Over has connected in seven of the last nine games on the road for the Mariners and 4-1 in their last five against a right-handed starting pitcher.

The Over is 5-0 for the Astros in their last five at home against a team with a winning record.

The Over has also hit in four of the last five meetings of these clubs at Minute Maid Park.

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