In what will be the first game ever with fans at SoFi Stadium it’s only right that both residents of the stadium – the Los Angeles Chargers and Los Angeles Rams – square off. Kickoff will be at 10 p.m. ET as these two teams begin their preseason slate. Below, we look at the Chargers vs. Rams odds and lines, and make our best NFL picks, predictions and bets.
Rams head coach Sean McVay has already said his team will play it safe in the preseason again, resting about 35 players in the opener. QB Matthew Stafford will take the preseason off and won’t make his debut with Los Angeles until Sept. 12 against the Bears.
The Chargers will keep QB Justin Herbert on the sideline as well as they’re resting a good portion of their starters against the Rams. They’ve had trouble staying healthy in recent years so first-year head coach Brandon Staley isn’t taking any chances with his most important players. The Chargers have all the talent to win the AFC West, they just need to stay healthy and play up to expectations.
Chargers at Rams odds, spread and lines
Odds via Tipico Sportsbook; access USA TODAY Sports’ betting odds for a full list. Lines last updated at 11 a.m. ET.
- Money line: Chargers -200 (bet $200 to win $100) | Rams +160 (bet $100 to win $160)
- Against the spread/ATS: No spread available at the time of publishing.
- Total: 32.5 (O: -110 | U: -110)
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Chargers at Rams odds, lines, predictions and picks
Prediction
Chargers 21, Rams 14
Money line
The Rams aren’t playing any of their starters as they continue to play it safe under McVay. They won’t even be playing their backup QB John Wolford, leaving those duties to Bryce Perkins and Devlin Hodges.
QB Justin Herbert won’t play in this one for the Chargers either, but they’ll have more of their top players out there than the Rams.
Bet the CHARGERS (-200) to win outright.
Against the spread
No spread was available at the time of publishing.
Over/Under
The Over/Under is set significantly lower than most games, in fact it’s the lowest total of the week. That’s because both teams are playing it safe and holding their top players out as a precaution.
Still, the backups will put enough points on the board to push the score over the total of 32.5 points. Take the OVER 32.5 (-110).
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