Minnesota Twins at Chicago White Sox odds, picks and prediction

Analyzing Wednesday’s Minnesota Twins at Chicago White Sox odds and lines, with MLB picks and predictions.

The Minnesota Twins (33-44) hope to even their road series against the Chicago White Sox (46-32) Wednesday. First pitch is scheduled for 8:10 p.m. ET at Guaranteed Rate Field. Let’s analyze BetMGM Sportsbook‘s lines around the Twins vs. White Sox odds with MLB picks and predictions.

Rookie RHP Bailey Ober is the projected starting pitcher for the Twins. He is 0-0 with a 4.64 ERA, 1.31 WHIP, 9.7 K/9 and 1.7 BB/9 in 21 1/3 IP over five starts.

Ober has not pitched more than 5 innings in any start this season. He allowed 4 runs on 6 hits and 2 walks in 4 1/3 innings against Cincinnati June 22 in his last outing.

RHP Dylan Cease is the projected starting pitcher for the White Sox. He is 6-3 with a 3.81 ERA, 1.31 WHIP, 11.4 K/9 and 3.8 BB/9 in 75 2/3 IP over 15 starts.

Cease faced the Twins May 11 receiving a no decision in a 9-3 win, allowing 3 runs on 5 hits and 2 walks with 7 strikeouts in 5 innings.

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Twins at White Sox odds, lines, picks and prediction

MLB odds courtesy of BetMGM; access USA TODAY Sports for a full list. Odds last updated at 1:11 p.m. ET.

  • Money line: Twins +105 (bet $100 to win $105) | White Sox -125 (bet $125 to win $100)
  • Against the spread/ATS: Twins +1.5 (-190) | Whit Sox -1.5 (+155)
  • Over/Under: 9 (O: -110 | U: -110)

Prediction

White Sox 6, Twins 4

Money line (ML)

The Twins had a four-game road win streak snapped Tuesday in the series opener. They are 16-21 on the road this season and only 15-28 against teams over .500. Minnesota is 1-6 against the Sox on the year and winless in four games in Chicago against them.

The White Sox’s 29 home wins are more than any other team except the San Diego Padres. They are 25-12 against teams in the AL Central and have won Cease’s last six home starts.

Take the WHITE SOX (-125).

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Run line/Against the spread (ATS)

The Twins are 16-21 ATS on the road this season and have covered the spread in just three of seven meetings with the White Sox.

The White Sox are 40-38 ATS overall but have only covered the spread once in their last 11 games. Seven of the nine wins they have had with Cease on the mound have been by at least two runs.

Take the WHITE SOX -1.5 (+155).

Over/Under (O/U)

The series opener went Over the projected total. Five of the last six, and eight of the last 11, have hit the Over for the Twins. Minnesota has the highest Over percentage in MLB at 66.2%.

Eight of the last 11 for the White Sox have also gone Over the projected total.

Take OVER 9 (-110).

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