Tampa Bay Rays at Chicago White Sox odds, picks and prediction

Analyzing Wednesday’s Tampa Bay Rays at Chicago White Sox odds and lines, with MLB picks and predictions.

The Tampa Bay Rays (43-25) and Chicago White Sox (42-25) close out a three-game series Wednesday. First pitch will be at 2:10 p.m. ET at Guaranteed Rate Field. Let’s analyze BetMGM Sportsbook‘s lines around the Rays vs. White Sox odds with MLB picks and predictions.

LHP Ryan Yarbrough is the projected starting pitcher for the Rays. He is 4-3 with a 3.63 ERA, 1.08 WHIP, 7.4 K/9 and 1.5 BB/9 through 72 IP spanning 9 starts and 4 relief appearances.

The Rays lefty has posted three straight quality starts away from home. Since 2019, he has registered a 3.38 ERA and 0.94 WHIP in road games.

RHP Lucas Giolito is the projected starter for the White Sox. He is 5-5 with a 3.81 ERA, 1.11 WHIP, 11.4 K/9 and 3.0 BB/9 in 75 2/3 IP over 13 starts.

The White Sox right-hander has gone 6-plus innings in 6 straight starts. He owns a 3.15 ERA over that stretch. He has registered a 3.20 ERA at home.

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Rays at White Sox odds, lines, picks and prediction

MLB odds courtesy of BetMGM; access USA TODAY Sports for a full list. Odds last updated at 11:20 a.m. ET.

  • Money line: Rays +110 (bet $100 to win $110) | White Sox -135 (bet $135 to win $100)
  • Against the spread/ATS: Rays +1.5 (-165) | White Sox -1.5 (+140)
  • Over/Under: 7.5 (O: -115 | U: -105)

Prediction

White Sox 4, Rays 3

Money line (ML)

Tampa Bay won Monday’s series opener and snapped a 4-game Chicago win streak. The White Sox returned the favor Tuesday and ended a 4-game streak for the Rays. Both clubs are in first place in their respective divisions.

The Rays offense has slumped over recent weeks, posting a .666 OPS since May 25. The Sox have closed out five of their last six home series with wins and are at their best against lefty pitching with an MLB-best .810 OPS.

BACK THE WHITE SOX (-135).

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Run line/Against the spread (ATS)

PASS on the run line. The low total (and a lean on the Under) make for little operating room.

Over/Under (O/U)

The Under is 3-0-1 the last 4 meetings between these two clubs. UNDER 7.5 (-105) is the slight lean for Wednesday. Respect the pitching and defense on a cool and dry get-away day game.

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