Cleveland Cavaliers at Philadelphia 76ers odds, picks and prediction

Previewing Saturday’s Cleveland Cavaliers at Philadelphia 76ers NBA odds and lines, with basketball picks, tips and predictions.

The Cleveland Cavaliers (12-21) travel to meet the Philadelphia 76ers (22-11) on Saturday for a 7 p.m. tip-off at Wells Fargo Center in Philadelphia. Below, we analyze the Cavaliers-76ers odds and lines, with NBA picks and predictions.

Cavaliers at 76ers: Odds, spread and lines

Odds via BetMGM; access USA TODAY Sports’ betting odds for a full list. Lines last updated at 5:05 a.m. ET.

  • Money line: Cavaliers +450 (bet $100 to win $450) | 76ers -650 (bet $650 to win $100)
  • Against the spread/ATS: Cavaliers +10.5 (-105) | 76ers -10.5 (-115)
  • Over/Under: 223.5 (O: -110 | U: -110)

Cavaliers at 76ers: Key injuries

Cavaliers

  • PG Matthew Dellavedova (abdomen) out
  • C Andre Drummond (coach’s decision) out
  • PF Kevin Love (calf) out
  • PF Larry Nance Jr. (finger) out
  • SF Taurean Prince (personal) out

76ers

  • SF Tobias Harris (knee) out

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Cavaliers at 76ers: Odds, lines, predictions and picks

Prediction

76ers 111, Cavaliers 96

Money line (ML)

The 76ers (-650) will cost you five and a half times your potential return betting them straight up, and that’s a poor long-term strategy, even against the struggling Cavaliers (+450). PASS.

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Against the spread (ATS)

The 76ERS -10.5 (-115) lost Tobias Harris to a right knee contusion Thursday against Dallas, and while an MRI came back clean, multiple reports have listed him out for Saturday.

Philly should still persevere, as they’re 4-1 SU across the past five, and 3-1 ATS in the previous four. They’ll also have revenge on their minds after losing 118-94 on the road against the Cavs on Dec. 27 as six-point favorites.

The Cavaliers +10.5 (-105) are a dismal 3-13 ATS across the past 16 road games, and 0-8 ATS in the past eight against teams with a winning overall record.

Over/Under (O/U)

UNDER 223.5 (-110) is the best play on the board. The Under has cashed in four straight for Philly, and the Under is also 4-0 in their past four as a favorite.  For Cleveland, the Under has cashed in five straight, while going 5-0 in their past five as an underdog.

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