Jacksonville Jaguars at Indianapolis Colts odds, picks and prediction

Previewing the Jacksonville Jaguars at Indianapolis Colts Week 17 betting odds and lines, with NFL betting picks, tips and predictions.

The NFL season has reached Week 17 and the Jacksonville Jaguars (1-14) visit the Indianapolis Colts (10-5), who have a division title and postseason berth on the line. Sunday’s kickoff is set for 4:25 p.m. ET at Lucas Oil Stadium in Indianapolis. Below, we preview the Jaguars-Colts betting odds and lines and make our NFL picks and predictions.

Jaguars at Colts: Betting odds, spread and lines

Odds via BetMGM; access USA TODAY Sports’ betting odds for a full list. Lines last updated Saturday at 12:54 a.m. ET.

  • Money line: Jaguars +750 (bet $100 to win $750) | Host -1100 (bet $1,100 to win $100)
  • Against the spread/ATS: Jaguars +14 (-110) | Host -14 (-110)
  • Over/Under: 49.5 (O: -110 | U: -110)

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Jaguars at Colts: Game notes

  • Jacksonville has lost 14 games in a row after a season-opening win.
  • Indianapolis must win and get some help to either win the AFC South or make the postseason as a wild-card team.
  • Colts QB Philip Rivers has 4,005 passing yards with 23 touchdowns and 10 interceptions, half the total he threw in 2019. He has passed for 4,000-plus yards eight seasons in a row.
  • Indy’s defense ranks eighth in total yards allowed per game (335.4 YPG) and 12th in points allowed per game (23.3 PPG).
  • The Jaguars have secured the No. 1 pick in the 2021 NFL Draft.

Jaguars at Colts: Key injuries

Jaguars

  • WR DJ Chark (shin) questionable
  • RB James Robinson (ankle) out

Colts

  • WR Michael Pittman Jr. questionable
  • S Khari Willis (concussion) out
  • CB Rock Ya-Sin (concussion) out

Jaguars at Colts: Odds, betting lines, predictions and picks

Prediction

Colts 31, Jaguars 13

Money line (?)

The Colts (-1100) have everything on the line and the Jags are waiting the season out. Jacksonville QB Mike Glennon, who will make his second consecutive start, was unable to get the offense going in last week’s 41-17 home loss to the Chicago Bears. That said, there is no point making a money line bet at -1100. You only win $0.91 for every $10 wagered. It’s more or less a sure thing but not worth your time. AVOID.

Against the spread (?)

The spread is a ridiculous 14 points, but the Jaguars have lost their last three games each by at least 21 points. The Colts have failed to cover the spread in their last two games but are 8-7 ATS on the season. Take the COLTS -14 (-110).

Over/Under (?)

The total is pretty high, although Jacksonville’s last two games have gone Over and five of the Colts’ last seven have gone Over. Indy’s defense is too good to let Glennon do much without wideout Robinson. The Colts will roll but will cruise to a win. So, they won’t score enough to make up for the Jags’  weak offense. Take UNDER 49.5 (-110).

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