Los Angeles Rams at Arizona Cardinals odds, picks and prediction

Previewing the Los Angeles Rams at Arizona Cardinals Week 13 betting odds and lines, with NFL betting picks, tips and predictions.

The Los Angeles Rams (7-4) and Arizona Cardinals (6-5) meet this weekend in an NFC West battle with playoff implications. Kickoff is at 4:05 p.m. ET Sunday at State Farm Stadium in Glendale. Below, we preview the Rams-Cardinals betting odds and lines and make our NFL picks and predictions.

Rams at Cardinals: Betting odds, spread and lines

Odds via BetMGM; access USA TODAY Sports’ betting odds for a full list. Lines last updated Friday at 1:45 p.m. ET.

  • Money line: Rams -152 (bet $152 to win $100) | Cardinals +130 (bet $100 to win $130)
  • Against the spread/ATS: Rams -2.5 (-115) | Cardinals +2.5 (-105)
  • Over/Under: 47.5 (O: -115 | U: -105)

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Rams at Cardinals: Game notes

  • The Rams have won six straight games against them Cardinals, outscoring 195-56 in the wins.
  • The Cardinals have the No. 2 offense in the league, while the Rams have the league’s No. 2 defense by total yards.
  • Rams QB Jared Goff has thrown 2 interceptions in each of his last two games and in three of his last four.
  • Cardinals QB Kyler Murray was held without a touchdown pass for the first time this season in Week 12.
  • The Rams are fourth in the league with 34 sacks but Murray has been sacked only 18 times this season.

Rams at Cardinals: Key injuries

Rams

  • OL Brian Allen (knee) questionable
  • DL Sebastian Joseph-Day (hip) doubtful

Cardinals

  • Justin Pugh (ankle) questionable
  • Jalen Thompson (ankle) doubtful

Rams at Cardinals: Odds, betting lines, predictions and picks

Prediction

Rams 28, Cardinals 25

Money line (?)

The Cardinals have lost three of four overall and are currently on a six-game losing streak against the Rams. They have not been as effective offensively the last two weeks and the Rams have a very good defense. Take the RAMS (-152).

Against the spread (?)

The Cardinals are 3-1 against the spread as underdogs this year, but with only a 2.5-point spread, it will be very hard for the Cardinals to cover and still lose. Take the RAMS -2.5 (-115) to win by at least 3 points.

Over/Under (?)

Both the Rams and the Cardinals are 3-8 against the O/U this season, but both teams can move the ball. The 47.5 projection is low. Take OVER 47.5 (-115).

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