Los Angeles Rams at Philadelphia Eagles odds, picks and best bets

Previewing the Los Angeles Rams and Philadelphia Eagles Week 2 betting odds and lines, with NFL betting picks, tips and best bets.

The Los Angeles Rams (1-0) are seeking another 2-0 start to the season Sunday as they travel to face the Philadelphia Eagles (0-1), who blew a 17-point lead in a 27-17 loss to the Washington Football Team in Week 1. Kickoff from Lincoln Financial Field is set for 1 p.m. ET. Below, we preview the Rams-Eagles betting odds and lines and make our NFL picks and best bets.

Rams at Eagles betting odds and lines

Odds via BetMGM; access USA TODAY Sports’ betting odds for a full list. Lines last updated Saturday at 2:35 p.m. ET.

  • Money line: Rams +110 (bet $100, win $110) | Eagles -128 (Bet $128, win $100)
  • Against the spread/ATS: Rams +2 (-110) | Eagles -2 (-110)
  • Over/Under: 45.5 (O: -110, U: -110)

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Rams at Eagles game notes

  • Rams head coach Sean McVay is 4-0 in 1 p.m. ET games.
  • The Eagles allowed eight sacks in Week 1, which is twice as many as any other team in the NFL.
  • The Rams are 0-6 straight up and against the spread in their last six games against the Eagles.
  • The Rams have won their first road game in each of the last three seasons.
  • The total went Under in the Rams’ season opener against the Dallas Cowboys, but Over in the Eagles’ 27-17 loss to Washington in Week 1.

Rams at Eagles key injuries

Rams

  • TE Gerald Everett (back) questionable

Eagles

  • WR Alshon Jeffery (foot) out
  • DE Brandon Graham (concussion) questionable
  • DE Derek Barnett (hamstring) questionable

Rams at Eagles: Odds, betting lines, picks and prediction

Prediction

Rams 24, Eagles 21

Money line (?)

This game is essentially a toss-up, as evidenced by the money line on both sides and the 2-point spread. The Rams will be facing a vastly different Eagles team than the one Washington beat in Week 1.

With the Eagles expected to have OT Lane Johnson, RB Miles Sanders and DT Javon Hargrave all healthy, they’ll be in better shape than they were in the season opener. Still, the Rams are healthy and coming off a statement win, boasting a balanced offensive attack and aggressive defense.

Take the RAMS (+110) to win outright.

Against the spread (?)

The Rams are 2-point underdogs over Philadelphia. Although the Eagles have had the Rams’ number, this is a very winnable game for Los Angeles, even with the Eagles healthier coming into Week 2.

The small spread has minimal impact, which is why I’m going with the RAMS +2 (-110) to cover the 1-point margin and still win in a close one.

Over/Under (?)

The Over/Under is lower for the Rams this week, but the total is higher than the Eagles saw in the season opener. At 45.5 points, it’s not overly high, but these teams both have strong defenses with dominant interior defenders and elite corners.

The offenses will get their points, but not enough to put the total Over 45.5. Take the UNDER 45.5 (-110).

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