San Francisco Giants at Arizona Diamondbacks odds, picks and best bets

Previewing Friday’s San Francisco Giants at Arizona Diamondbacks sports betting odds and lines, with MLB betting picks, tips and best bets.

The San Francisco Giants (15-18) and Arizona Diamondbacks (13-19) kick off a three-game set Friday at Chase Field with a 9:40 p.m. ET first pitch. We analyze the Giants-Diamondbacks MLB betting odds and lines, with picks and best bets.

Giants at Diamondbacks: Projected starting pitchers

LHP Tyler Anderson vs. RHP Zac Gallen

Anderson has posted a 1-1 record, 3.45 ERA, 1.21 WHIP and 21 strikeouts over 31 1/3 innings across five starts and two relief appearances.

  • Anderson allowed one unearned run, three hits and no walks with four strikeouts in a complete-game victory last Saturday against the Diamondbacks for his first-career complete game.
  • Anderson threw 69 of his 103 pitches for strikes, including first-pitch strikes to 21 of the 32 batters he faced.

Gallen has not factored into a decision in six starts, posting a 2.25 ERA, 1.06 WHIP and 42 strikeouts across 36 innings with 12 walks allowed.

  • Gallen was on the short end in that complete game by Anderson, allowing one earned run, three hits and four walks with six strikeouts over six innings in a quality start.
  • Gallen has turned in five consecutive quality starts, yielding just eight earned runs in 32 innings during the stretch.

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Giants at Diamondbacks: Key injuries

(Get the latest injury news here.)

Giants

  • OF Austin Slater (groin) out

Diamondbacks

  • RP Andrew Chafin (finger) out

Also see: BaseballHQ Fantasy Baseball

Giants at Diamondbacks: Odds, lines, picks and betting tips

MLB odds courtesy of BetMGM; access USA TODAY Sports for a full list. Odds last updated at 11:18 a.m. ET.

Prediction

Diamondbacks 4, Giants 2

Moneyline (ML)

The DIAMONDBACKS (-162) are a solid play behind Gallen, who has been tremendously efficient this season. He has allowed two or fewer earned runs in each of his six outings, and Arizona is 4-2 across his six starts. He’ll get revenge against the Anderson and the Giants (+145) in this one at home.

New to sports betting? A $10 bet on the Diamondbacks returns a profit of $6.17 if they win, while a winning $10 wager on the Giants fetches a return of $14.50.

Run line/Against the spread (ATS)

DIAMONDBACKS (-1.5, +125) is a tempting play at this price, even though they’re facing a pitcher who completely shut them down last time. Anderson has proven over his career that he isn’t terribly consistent. In fact, in the two outings previous to his CG, he allowed 9 earned runs, 13 hits and 4 walks in just 10 innings in a pair of no-decisions. TAKE ARIZONA, but go lightly.

Over/Under (O/U)

The UNDER 8.5 (-110) cashed in all three meetings last weekend in San Francisco, as we saw an average of seven runs in the three-game set. Look for more solid pitching against some subpar offensive production.

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