The 49ers defense had their worst game of the season last week when they allowed 46 points and 465 yards to the Saints. The Falcons’ offense can be explosive, but this season they haven’t reached their potential thanks to inexperience and injuries at key spots. The defense could have some issues with the amount of injuries they’re dealing with as well.

Here are the six players to watch:

CB Emmanuel Moseley

With Richard Sherman out on Sunday, Moseley will step back into a starting role. He’ll face a tough challenge in coverage when he gets lined up against Julio Jones. The All-Pro receiver has dominated this season despite the offense falling apart around him. He has 69 receptions for 1,016 yards and four touchdown receptions. Moseley had success earlier in the season when taking over for Ahkello Witherspoon, but he never had to deal with a receiver the quality of Jones. How Moseley fares back in the starting lineup will play a big role in how well the 49ers’ defense adapts.