4 49ers players who could make an impact vs. Cardinals in wake of injuries

These players will play a more prominent role than normal because of injuries.

The San Francisco 49ers will be without several players on Sunday when they take on the Arizona Cardinals. As a result, other players will have the opportunity to step up and make an impact on the game.

Here are some who could stand out against the Cardinals.

WR Deebo Samuel

Mark J. Rebilas-USA TODAY Sports

Tight end George Kittle is out and receiver Emmanuel Sanders might not. Even if he does, he will be very limited. That will make Samuel QB Jimmy Garoppolo’s top target. In the 49ers’ loss to the Seattle Seahawks, Samuel had a career-high eight receptions for 112 yards.

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